1 Response_reg#1
5-104 aa · 100 aa · 15.2% of protein
Raw token
Response_reg:5:2.9e-29:104:100:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ACD536_RS00630
Histidine kinase, Hybrid
Clostridioides difficile · GCF_041537345
ClassHKTypeHybridLength658 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_041537345#ACD536_RS00630Stable P2CS identifier used across views.
GenomeGCF_041537345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regANTARH_kinase_NHisKA_2HATPase_c
Protein length658 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage453 / 658 aa (68.8%)Merged over positioned domains only.
Domain description1 Response_reg,1 ANTAR,1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation5 items
2 ANTAR#2
138-186 aa · 49 aa · 7.4% of protein
Raw token
ANTAR:138:4.16e-20:186:49:493 H_kinase_N#3
201-331 aa · 131 aa · 19.9% of protein
Raw token
H_kinase_N:201:4.9e-36:331:132:1394 HisKA_2#4
465-539 aa · 75 aa · 11.4% of protein
Raw token
HisKA_2:465:1.46e-16:539:76:765 HATPase_c#5
559-656 aa · 98 aa · 14.9% of protein
Raw token
HATPase_c:559:0.0000000776:656:114:109- Raw architecture: Response_reg:5:2.9e-29:104:100:111#ANTAR:138:4.16e-20:186:49:49#H_kinase_N:201:4.9e-36:331:132:139#HisKA_2:465:1.46e-16:539:76:76#HATPase_c:559:0.0000000776:656:114:109
- Domain description: 1 Response_reg,1 ANTAR,1 H_kinase_N,1 HisKA_2,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_041537345::NZ_JBGOPJ010000001.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span123524-125500Genomic interval covered by the local TCS group.
Identifiers
Old locus tagACD536_00630RefSeq proteinWP_372556471.1
Context group ID
GCF_041537345::NZ_JBGOPJ010000001.1::G00004Context members
ACD536_RS00630
Partner locus tags
ACD536_RS00630
Partner old locus tags
ACD536_00630
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_372556471.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagACD536_RS00630Primary locus identifier stored in the genes table.
Old locus tagACD536_00630Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBGOPJ010000001.1Sequence record reported by the local genomic context database.
Genomic interval123 524-125 500 nt1 977 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span123 524-125 500 ntGCF_041537345::NZ_JBGOPJ010000001.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_041537345::NZ_JBGOPJ010000001.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBGOPJ010000001.1All displayed genes belong to this local TCS context.
Neighborhood span123 524-125 500 nt1 977 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
123 524 nt125 500 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
ACD536_RS00630GCF_041537345#ACD536_RS00630
HKHybridCurrent focus
123 524-125 500 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_041537345#ACD536_RS00630The current gene is the representative for this cluster.
PFAM architectureResponse_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0878348
Simplified PFAM architecture for HKOC_0878348
PFAM domain coverage: 466 / 658 aa (70.8%)
1 aa658 aa
Response_regANTARGAF_PdtaSHisKA_2HATPase_c
- Simplified architecture: Response_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c
- Raw architecture: Response_reg[5-115] | ANTAR[134-186] | GAF_PdtaS[195-330] | HisKA_2[465-536] | HATPase_c[562-655]
- Domain count: 5
- Matched identifier: HKOC_0878348
- Positioned domains: Response_reg 5-115 ; ANTAR 134-186 ; GAF_PdtaS 195-330 ; HisKA_2 465-536 ; HATPase_c 562-655
Cluster members and taxonomy
Representative gene: GCF_041537345#ACD536_RS00630
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_041537345
AssemblyASM4153734v1 · Contighaploid
Genome composition4 141 476 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 93 · HK 44 · RR 48CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key