Gene detail

AB5805_RS05255

Histidine kinase, Classic

Blautia wexlerae · GCF_040926725

ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_040926725#AB5805_RS05255Stable P2CS identifier used across views.
GenomeGCF_040926725Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1047992Run 6 · 34 sequences · id 100% · cov 80%
External referencesWP_022380184.1 · A0A174TEV0 · MIST4 AB5805_RS05255RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage496 / 601 aa (82.5%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa601 aa
dCache_1: 48-289 aa (242 aa)1HAMP: 308-377 aa (70 aa)2His_kinase: 393-471 aa (79 aa)3HATPase_c: 487-591 aa (105 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
48-289 aa · 242 aa · 40.3% of protein
Raw tokendCache_1:48:5.95e-18:289:246:195
2 HAMP#2
308-377 aa · 70 aa · 11.6% of protein
Raw tokenHAMP:308:0.00000000000000156:377:70:69
3 His_kinase#3
393-471 aa · 79 aa · 13.1% of protein
Raw tokenHis_kinase:393:5.4e-37:471:79:80
4 HATPase_c#4
487-591 aa · 105 aa · 17.5% of protein
Raw tokenHATPase_c:487:0.0000000000000125:591:109:109
  • Raw architecture: dCache_1:48:5.95e-18:289:246:195#HAMP:308:0.00000000000000156:377:70:69#His_kinase:393:5.4e-37:471:79:80#HATPase_c:487:0.0000000000000125:591:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_040926725::NZ_JBCOHO010000011.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span70017-73438Genomic interval covered by the local TCS group.
Context group IDGCF_040926725::NZ_JBCOHO010000011.1::G00020
Context members
AB5805_RS05250AB5805_RS05255
Partner locus tags
AB5805_RS05250AB5805_RS05255
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022380184.1Primary protein accession used for annex mappings.
UniProt accessionA0A174TEV0Primary UniProt accession resolved in the annex database.
UniProt IDA0A174TEV0_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAB5805_RS05255Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JBCOHO010000011.1Sequence record reported by the local genomic context database.
Genomic interval71 633-73 438 nt1 806 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span70 017-73 438 ntGCF_040926725::NZ_JBCOHO010000011.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_040926725::NZ_JBCOHO010000011.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBCOHO010000011.1All displayed genes belong to this local TCS context.
Neighborhood span70 017-73 438 nt3 422 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
70 017 nt73 438 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

AB5805_RS05250GCF_040926725#AB5805_RS05250
RRunclassified

70 017-71 636 nt · Forward (+)

RefSeq WP_022380183.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1047992Run 6 · HK · 34 sequences
Representative sequenceGCF_001404755#ARA24_RS11455Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1047992

Simplified PFAM architecture for HKOC_1047992

PFAM domain coverage: 479 / 601 aa (79.7%)

1 aa601 aa
dCache_1: 49-289 aadCache_1HAMP: 324-377 aaHAMPHis_kinase: 393-471 aaHis_kinaseHATPase_c: 487-591 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[49-289] | HAMP[324-377] | His_kinase[393-471] | HATPase_c[487-591]
  • Domain count: 4
  • Matched identifier: HKOC_1047992
  • Positioned domains: dCache_1 49-289 ; HAMP 324-377 ; His_kinase 393-471 ; HATPase_c 487-591
Cluster members and taxonomy
Visualization

Representative gene: GCF_001404755#ARA24_RS11455

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 418 240 · GCF_040926725
AssemblyASM4092672v1 · Scaffoldhaploid
Genome composition4 195 638 bp · 41,0% GCBlautia wexlerae
Signal transduction countsGenes 125 · HK 60 · RR 63CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key