Gene detail

V8R73_RS02535

Histidine kinase, Classic

Eubacterium ramulus · GCF_037068565

ClassHKTypeClassicLength489 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_037068565#V8R73_RS02535Stable P2CS identifier used across views.
GenomeGCF_037068565Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae; Eubacterium
Selected clusterHKOC_1541546Run 6 · 5 sequences · id 100% · cov 80%
External referencesWP_021738281.1 · A0A173S7D4 · MIST4 V8R73_RS02535RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length489 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 489 aa (50.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa489 aa
HAMP: 171-242 aa (72 aa)1HisKA: 267-334 aa (68 aa)2HATPase_c: 379-486 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
171-242 aa · 72 aa · 14.7% of protein
Raw tokenHAMP:171:0.00000000000611:242:72:69
2 HisKA#2
267-334 aa · 68 aa · 13.9% of protein
Raw tokenHisKA:267:0.00000000000000476:334:68:64
3 HATPase_c#3
379-486 aa · 108 aa · 22.1% of protein
Raw tokenHATPase_c:379:3.73e-19:486:109:109
  • Raw architecture: HAMP:171:0.00000000000611:242:72:69#HisKA:267:0.00000000000000476:334:68:64#HATPase_c:379:3.73e-19:486:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_037068565::NZ_JBAMSF010000004.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span126660-128959Genomic interval covered by the local TCS group.
Identifiers
Old locus tagV8R73_02535RefSeq proteinWP_021738281.1
Context group IDGCF_037068565::NZ_JBAMSF010000004.1::G00003
Context members
V8R73_RS02530V8R73_RS02535
Partner locus tags
V8R73_RS02530V8R73_RS02535
Partner old locus tags
V8R73_02530V8R73_02535
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021738281.1Primary protein accession used for annex mappings.
UniProt accessionA0A173S7D4Primary UniProt accession resolved in the annex database.
UniProt IDA0A173S7D4_EUBRADisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagV8R73_RS02535Primary locus identifier stored in the genes table.
Old locus tagV8R73_02535Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JBAMSF010000004.1Sequence record reported by the local genomic context database.
Genomic interval127 490-128 959 nt1 470 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span126 660-128 959 ntGCF_037068565::NZ_JBAMSF010000004.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_037068565::NZ_JBAMSF010000004.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JBAMSF010000004.1All displayed genes belong to this local TCS context.
Neighborhood span126 660-128 959 nt2 300 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
126 660 nt128 959 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

V8R73_RS02530GCF_037068565#V8R73_RS02530
RROmpR

126 660-127 334 nt · Forward (+)

Old locus V8R73_02530RefSeq WP_021738280.1
V8R73_RS02535GCF_037068565#V8R73_RS02535
HKClassicCurrent focus

127 490-128 959 nt · Forward (+)

Old locus V8R73_02535RefSeq WP_021738281.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1541546Run 6 · HK · 5 sequences
Representative sequenceGCF_000469345#HMPREF0373_RS03780Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1541546

Simplified PFAM architecture for HKOC_1541546

PFAM domain coverage: 228 / 489 aa (46.6%)

1 aa489 aa
HAMP: 188-241 aaHAMPHisKA: 267-332 aaHisKAHATPase_c: 379-486 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-241] | HisKA[267-332] | HATPase_c[379-486]
  • Domain count: 3
  • Matched identifier: HKOC_1541546
  • Positioned domains: HAMP 188-241 ; HisKA 267-332 ; HATPase_c 379-486
Cluster members and taxonomy
Visualization

Representative gene: GCF_000469345#HMPREF0373_RS03780

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 490 · GCF_037068565
AssemblyASM3706856v1 · Contighaploid
Genome composition3 105 303 bp · 43,5% GCEubacterium ramulus
Signal transduction countsGenes 58 · HK 29 · RR 26CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyEubacteriaceaeGenusEubacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Eubacteriaceae7Eubacterium

Related genes

Preview from the same derived genome key