1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw token
HisKA:199:0.00000000129:258:60:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SQ528_RS02720
Histidine kinase, Classic
Clostridioides difficile · GCF_034188315
ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_034188315#SQ528_RS02720Stable P2CS identifier used across views.
GenomeGCF_034188315Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa417 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw token
HATPase_c:304:2.2e-21:410:107:109- Raw architecture: HisKA:199:0.00000000129:258:60:64#HATPase_c:304:2.2e-21:410:107:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_034188315::NZ_JAXHRE010000004.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15111-17067Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSQ528_02720RefSeq proteinWP_011861225.1
Context group ID
GCF_034188315::NZ_JAXHRE010000004.1::G00013Context members
SQ528_RS02720SQ528_RS02725
Partner locus tags
SQ528_RS02720SQ528_RS02725
Partner old locus tags
SQ528_02720SQ528_02725
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_011861225.1Primary protein accession used for annex mappings.
UniProt accessionQ18BY5Primary UniProt accession resolved in the annex database.
UniProt IDQ18BY5_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSQ528_RS02720Primary locus identifier stored in the genes table.
Old locus tagSQ528_02720Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAXHRE010000004.1Sequence record reported by the local genomic context database.
Genomic interval15 111-16 364 nt1 254 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span15 111-17 067 ntGCF_034188315::NZ_JAXHRE010000004.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_034188315::NZ_JAXHRE010000004.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAXHRE010000004.1All displayed genes belong to this local TCS context.
Neighborhood span15 111-17 067 nt1 957 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 111 nt17 067 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SQ528_RS02720GCF_034188315#SQ528_RS02720
HKClassicCurrent focus
15 111-16 364 nt · Reverse (-)
SQ528_RS02725GCF_034188315#SQ528_RS02725
RROmpR
16 342-17 067 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS08040Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2293407
Simplified PFAM architecture for HKOC_2293407
PFAM domain coverage: 169 / 417 aa (40.5%)
1 aa417 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[196-258] | HATPase_c[305-410]
- Domain count: 2
- Matched identifier: HKOC_2293407
- Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS08040
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_034188315
AssemblyASM3418831v1 · Contighaploid
Genome composition4 239 228 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key