1 H_kinase_N#1
12-142 aa · 131 aa · 30.2% of protein
Raw token
H_kinase_N:12:9.85e-37:142:132:139P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK61_RS11875
Histidine kinase, Classic
Clostridioides difficile · GCF_033840955
ClassHKTypeClassicLength434 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_033840955#SIK61_RS11875Stable P2CS identifier used across views.
GenomeGCF_033840955Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
H_kinase_NHisKA_2HATPase_c
Protein length434 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage265 / 434 aa (61.1%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa434 aa
Domain-by-domain annotation3 items
2 HisKA_2#2
276-350 aa · 75 aa · 17.3% of protein
Raw token
HisKA_2:276:2.11e-16:350:76:763 HATPase_c#3
370-428 aa · 59 aa · 13.6% of protein
Raw token
HATPase_c:370:0.0000367:428:59:109- Raw architecture: H_kinase_N:12:9.85e-37:142:132:139#HisKA_2:276:2.11e-16:350:76:76#HATPase_c:370:0.0000367:428:59:109
- Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_033840955::NZ_JAWXRW010000287.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2569-4438Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK61_11865RefSeq proteinWP_320062486.1
Context group ID
GCF_033840955::NZ_JAWXRW010000287.1::G00013Context members
SIK61_RS11870SIK61_RS11875
Partner locus tags
SIK61_RS11870SIK61_RS11875
Partner old locus tags
SIK61_11860SIK61_11865
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_320062486.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK61_RS11875Primary locus identifier stored in the genes table.
Old locus tagSIK61_11865Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXRW010000287.1Sequence record reported by the local genomic context database.
Genomic interval3 137-4 438 nt1 302 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 569-4 438 ntGCF_033840955::NZ_JAWXRW010000287.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033840955::NZ_JAWXRW010000287.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXRW010000287.1All displayed genes belong to this local TCS context.
Neighborhood span2 569-4 438 nt1 870 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 569 nt4 438 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SIK61_RS11870GCF_033840955#SIK61_RS11870
RRAmiR_NasR
2 569-3 144 nt · Forward (+)
SIK61_RS11875GCF_033840955#SIK61_RS11875
HKClassicCurrent focus
3 137-4 438 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_033840955#SIK61_RS11875The current gene is the representative for this cluster.
PFAM architectureGAF_PdtaS + HisKA_22 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2136219
Simplified PFAM architecture for HKOC_2136219
PFAM domain coverage: 208 / 434 aa (47.9%)
1 aa434 aa
GAF_PdtaSHisKA_2
- Simplified architecture: GAF_PdtaS + HisKA_2
- Raw architecture: GAF_PdtaS[6-141] | HisKA_2[276-347]
- Domain count: 2
- Matched identifier: HKOC_2136219
- Positioned domains: GAF_PdtaS 6-141 ; HisKA_2 276-347
Cluster members and taxonomy
Representative gene: GCF_033840955#SIK61_RS11875
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033840955
AssemblyASM3384095v1 · Contighaploid
Genome composition3 759 897 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 86 · HK 36 · RR 47CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key