1 HAMP#1
2-57 aa · 56 aa · 18.5% of protein
Raw token
HAMP:2:0.00000000227:57:56:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SIK61_RS02330
Histidine kinase, Classic
Clostridioides difficile · GCF_033840955
ClassHKTypeClassicLength303 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_033840955#SIK61_RS02330Stable P2CS identifier used across views.
GenomeGCF_033840955Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length303 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage225 / 303 aa (74.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa303 aa
Domain-by-domain annotation3 items
2 HisKA#2
82-146 aa · 65 aa · 21.5% of protein
Raw token
HisKA:82:0.0000000000227:146:65:643 HATPase_c#3
192-295 aa · 104 aa · 34.3% of protein
Raw token
HATPase_c:192:4.99e-19:295:108:109- Raw architecture: HAMP:2:0.00000000227:57:56:69#HisKA:82:0.0000000000227:146:65:64#HATPase_c:192:4.99e-19:295:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_033840955::NZ_JAWXRW010000019.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3542-5576Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSIK61_02330RefSeq proteinWP_320062286.1
Context group ID
GCF_033840955::NZ_JAWXRW010000019.1::G00008Context members
SIK61_RS02330SIK61_RS02335
Partner locus tags
SIK61_RS02330SIK61_RS02335
Partner old locus tags
SIK61_02330SIK61_02335
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_320062286.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSIK61_RS02330Primary locus identifier stored in the genes table.
Old locus tagSIK61_02330Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWXRW010000019.1Sequence record reported by the local genomic context database.
Genomic interval3 542-4 453 nt912 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 542-5 576 ntGCF_033840955::NZ_JAWXRW010000019.1::G00008
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_033840955::NZ_JAWXRW010000019.1::G00008Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWXRW010000019.1All displayed genes belong to this local TCS context.
Neighborhood span3 542-5 576 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 542 nt5 576 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SIK61_RS02330GCF_033840955#SIK61_RS02330
HKClassicCurrent focus
3 542-4 453 nt · Reverse (-)
SIK61_RS02335GCF_033840955#SIK61_RS02335
RROmpR
4 905-5 576 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_033840955#SIK61_RS02330The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2884425
Simplified PFAM architecture for HKOC_2884425
PFAM domain coverage: 217 / 303 aa (71.6%)
1 aa303 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[7-56] | HisKA[83-146] | HATPase_c[193-295]
- Domain count: 3
- Matched identifier: HKOC_2884425
- Positioned domains: HAMP 7-56 ; HisKA 83-146 ; HATPase_c 193-295
Cluster members and taxonomy
Representative gene: GCF_033840955#SIK61_RS02330
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_033840955
AssemblyASM3384095v1 · Contighaploid
Genome composition3 759 897 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 86 · HK 36 · RR 47CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key