Gene detail

E7B23_RS12090

Histidine kinase, Classic

Clostridium sp. · GCF_032486475

ClassHKTypeClassicLength621 aaTM0ValidatedNoCompleteYesContexttetrad
Gene IDGCF_032486475#E7B23_RS12090Stable P2CS identifier used across views.
GenomeGCF_032486475Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Clostridiaceae; Clostridium
Selected clusterHKOC_0970093Run 6 · 31 sequences · id 100% · cov 80%
External referencesWP_051195978.1 · MIST4 E7B23_RS12090RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length621 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage357 / 621 aa (57.5%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa621 aa
HAMP: 185-253 aa (69 aa)1PAS: 270-376 aa (107 aa)2HisKA: 385-452 aa (68 aa)3HATPase_c: 498-610 aa (113 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
185-253 aa · 69 aa · 11.1% of protein
Raw tokenHAMP:185:0.000000118:253:69:69
2 PAS#2
270-376 aa · 107 aa · 17.2% of protein
Raw tokenPAS:270:0.0000000416:376:110:113
3 HisKA#3
385-452 aa · 68 aa · 11.0% of protein
Raw tokenHisKA:385:1.32e-21:452:68:64
4 HATPase_c#4
498-610 aa · 113 aa · 18.2% of protein
Raw tokenHATPase_c:498:1.63e-26:610:113:109
  • Raw architecture: HAMP:185:0.000000118:253:69:69#PAS:270:0.0000000416:376:110:113#HisKA:385:1.32e-21:452:68:64#HATPase_c:498:1.63e-26:610:113:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltetradGCF_032486475::NZ_JAWELC010000007.1::G00025
Group size44 locus tags listed below.
HK / RR2 / 2Counts resolved for the local TCS neighborhood.
Context span131560-137464Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE7B23_12105RefSeq proteinWP_051195978.1
Context group IDGCF_032486475::NZ_JAWELC010000007.1::G00025
Context members
E7B23_RS12080E7B23_RS12085E7B23_RS12090E7B23_RS12095
Partner locus tags
E7B23_RS12080E7B23_RS12085E7B23_RS12090E7B23_RS12095
Partner old locus tags
E7B23_12095E7B23_12100E7B23_12105E7B23_12110

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_051195978.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE7B23_RS12090Primary locus identifier stored in the genes table.
Old locus tagE7B23_12105Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAWELC010000007.1Sequence record reported by the local genomic context database.
Genomic interval134 959-136 824 nt1 866 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span131 560-137 464 ntGCF_032486475::NZ_JAWELC010000007.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_032486475::NZ_JAWELC010000007.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltetradNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAWELC010000007.1All displayed genes belong to this local TCS context.
Neighborhood span131 560-137 464 nt5 905 nt
Members41 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
131 560 nt137 464 nt
Neighborhood gene cards

4 genes in the current local neighborhood.

E7B23_RS12080GCF_032486475#E7B23_RS12080
HKClassic

131 560-134 277 nt · Forward (+)

Old locus E7B23_12095RefSeq WP_316090129.1
E7B23_RS12085GCF_032486475#E7B23_RS12085
RROmpR

134 246-134 938 nt · Forward (+)

Old locus E7B23_12100RefSeq WP_081663676.1
E7B23_RS12090GCF_032486475#E7B23_RS12090
HKClassicCurrent focus

134 959-136 824 nt · Forward (+)

Old locus E7B23_12105RefSeq WP_051195978.1
E7B23_RS12095GCF_032486475#E7B23_RS12095
RRunclassified

136 802-137 464 nt · Forward (+)

Old locus E7B23_12110RefSeq WP_027098533.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0970093Run 6 · HK · 31 sequences
Representative sequenceGCF_000424025#G594_RS18790Use this link to inspect the representative gene detail.
PFAM architecturePAS + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0970093

Simplified PFAM architecture for HKOC_0970093

PFAM domain coverage: 256 / 621 aa (41.2%)

1 aa621 aa
PAS: 269-344 aaPASHisKA: 385-452 aaHisKAHATPase_c: 499-610 aaHATPase_c
PASHisKAHATPase_c
  • Simplified architecture: PAS + HisKA + HATPase_c
  • Raw architecture: PAS[269-344] | HisKA[385-452] | HATPase_c[499-610]
  • Domain count: 3
  • Matched identifier: HKOC_0970093
  • Positioned domains: PAS 269-344 ; HisKA 385-452 ; HATPase_c 499-610
Cluster members and taxonomy
Visualization

Representative gene: GCF_000424025#G594_RS18790

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 506 · GCF_032486475
AssemblyASM3248647v1 · Contighaploid
Genome composition3 547 046 bp · 30,0% GCClostridium sp.
Signal transduction countsGenes 74 · HK 39 · RR 33CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyClostridiaceaeGenusClostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Clostridiaceae7Clostridium

Related genes

Preview from the same derived genome key