Gene detail

PSL78_RS00895

Histidine kinase, Classic

Clostridioides difficile · GCF_028596515

ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_028596515#PSL78_RS00895Stable P2CS identifier used across views.
GenomeGCF_028596515Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0878348Run 6 · 1724 sequences · id 100% · cov 80%
External referencesWP_003435429.1 · Q187M1 · MIST4 PSL78_RS00895RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for PSL78_RS00895
Domain-by-domain annotation3 items
1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw tokenH_kinase_N:12:1.53e-36:142:132:139
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw tokenHisKA_2:276:2.46e-16:350:76:76
3 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw tokenHATPase_c:370:0.0000000689:467:114:109
  • Raw architecture: H_kinase_N:12:1.53e-36:142:132:139#HisKA_2:276:2.46e-16:350:76:76#HATPase_c:370:0.0000000689:467:114:109
  • Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_028596515::NZ_JAQRIF010000001.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span185187-187164Genomic interval covered by the local TCS group.
Identifiers
Old locus tagPSL78_00895RefSeq proteinWP_003435429.1
Context group IDGCF_028596515::NZ_JAQRIF010000001.1::G00020
Context members
PSL78_RS00895PSL78_RS00900
Partner locus tags
PSL78_RS00895PSL78_RS00900
Partner old locus tags
PSL78_00895PSL78_00900
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003435429.1Primary protein accession used for annex mappings.
UniProt accessionQ187M1Primary UniProt accession resolved in the annex database.
UniProt IDQ187M1_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagPSL78_RS00895Primary locus identifier stored in the genes table.
Old locus tagPSL78_00895Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAQRIF010000001.1Sequence record reported by the local genomic context database.
Genomic interval185 187-186 596 nt1 410 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span185 187-187 164 ntGCF_028596515::NZ_JAQRIF010000001.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_028596515::NZ_JAQRIF010000001.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAQRIF010000001.1All displayed genes belong to this local TCS context.
Neighborhood span185 187-187 164 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
185 187 nt187 164 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

PSL78_RS00895GCF_028596515#PSL78_RS00895
HKClassicCurrent focus

185 187-186 596 nt · Reverse (-)

Old locus PSL78_00895RefSeq WP_003435429.1
PSL78_RS00900GCF_028596515#PSL78_RS00900
RRAmiR_NasR

186 589-187 164 nt · Reverse (-)

Old locus PSL78_00900RefSeq WP_003423977.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0878348Run 6 · HK · 1724 sequences
Representative sequenceGCF_041537345#ACD536_RS00630Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0878348

Simplified PFAM architecture for HKOC_0878348

PFAM domain coverage: 466 / 658 aa (70.8%)

1 aa658 aa
Response_reg: 5-115 aaResponse_regANTAR: 134-186 aaANTARGAF_PdtaS: 195-330 aaGAF_PdtaSHisKA_2: 465-536 aaHisKA_2HATPase_c: 562-655 aaHATPase_c
Response_regANTARGAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: Response_reg + ANTAR + GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: Response_reg[5-115] | ANTAR[134-186] | GAF_PdtaS[195-330] | HisKA_2[465-536] | HATPase_c[562-655]
  • Domain count: 5
  • Matched identifier: HKOC_0878348
  • Positioned domains: Response_reg 5-115 ; ANTAR 134-186 ; GAF_PdtaS 195-330 ; HisKA_2 465-536 ; HATPase_c 562-655
Cluster members and taxonomy
Visualization

Representative gene: GCF_041537345#ACD536_RS00630

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_028596515
AssemblyASM2859651v1 · Contighaploid
Genome composition4 313 127 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 111 · HK 53 · RR 58CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key