Gene detail

PNW18_RS01245

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_028327425

ClassHKTypeClassicLength463 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_028327425#PNW18_RS01245Stable P2CS identifier used across views.
GenomeGCF_028327425Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1796020Run 6 · 20 sequences · id 100% · cov 80%
External referencesWP_009243919.1 · A0AAJ3KLH8 · MIST4 PNW18_RS01245RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length463 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 463 aa (52.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa463 aa
HAMP: 166-233 aa (68 aa)1HisKA: 237-302 aa (66 aa)2HATPase_c: 350-460 aa (111 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
166-233 aa · 68 aa · 14.7% of protein
Raw tokenHAMP:166:0.000000000202:233:68:69
2 HisKA#2
237-302 aa · 66 aa · 14.3% of protein
Raw tokenHisKA:237:0.000000000000115:302:66:64
3 HATPase_c#3
350-460 aa · 111 aa · 24.0% of protein
Raw tokenHATPase_c:350:1.05e-32:460:111:109
  • Raw architecture: HAMP:166:0.000000000202:233:68:69#HisKA:237:0.000000000000115:302:66:64#HATPase_c:350:1.05e-32:460:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_028327425::NZ_JAQMLK010000001.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span249418-251539Genomic interval covered by the local TCS group.
Identifiers
Old locus tagPNW18_01245RefSeq proteinWP_009243919.1
Context group IDGCF_028327425::NZ_JAQMLK010000001.1::G00016
Context members
PNW18_RS01245PNW18_RS01250
Partner locus tags
PNW18_RS01245PNW18_RS01250
Partner old locus tags
PNW18_01245PNW18_01250
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009243919.1Primary protein accession used for annex mappings.
UniProt accessionA0AAJ3KLH8Primary UniProt accession resolved in the annex database.
UniProt IDA0AAJ3KLH8_MEDGNDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagPNW18_RS01245Primary locus identifier stored in the genes table.
Old locus tagPNW18_01245Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAQMLK010000001.1Sequence record reported by the local genomic context database.
Genomic interval249 418-250 809 nt1 392 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span249 418-251 539 ntGCF_028327425::NZ_JAQMLK010000001.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_028327425::NZ_JAQMLK010000001.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAQMLK010000001.1All displayed genes belong to this local TCS context.
Neighborhood span249 418-251 539 nt2 122 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
249 418 nt251 539 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

PNW18_RS01245GCF_028327425#PNW18_RS01245
HKClassicCurrent focus

249 418-250 809 nt · Reverse (-)

Old locus PNW18_01245RefSeq WP_009243919.1
PNW18_RS01250GCF_028327425#PNW18_RS01250
RROmpR

250 847-251 539 nt · Reverse (-)

Old locus PNW18_01250RefSeq WP_009243920.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1796020Run 6 · HK · 20 sequences
Representative sequenceGCF_000507805#HMPREF1201_RS03315Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1796020

Simplified PFAM architecture for HKOC_1796020

PFAM domain coverage: 176 / 463 aa (38.0%)

1 aa463 aa
HisKA: 238-302 aaHisKAHATPase_c: 350-460 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[238-302] | HATPase_c[350-460]
  • Domain count: 2
  • Matched identifier: HKOC_1796020
  • Positioned domains: HisKA 238-302 ; HATPase_c 350-460
Cluster members and taxonomy
Visualization

Representative gene: GCF_000507805#HMPREF1201_RS03315

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_028327425
AssemblyASM2832742v1 · Scaffoldhaploid
Genome composition3 484 075 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 86 · HK 41 · RR 44CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key