Gene detail

PG027_RS14250

Histidine kinase, CheA

Escherichia coli · GCF_027688815

ClassHKTypeCheALength662 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_027688815#PG027_RS14250Stable P2CS identifier used across views.
GenomeGCF_027688815Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_0868779Run 6 · 11857 sequences · id 100% · cov 80% · representative
External referencesWP_270589834.1 · MIST4 PG027_RS14250RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length662 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage415 / 662 aa (62.7%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa662 aa
Hpt: 7-93 aa (87 aa)1H-kinase_dim: 263-324 aa (62 aa)2HATPase_c: 371-508 aa (138 aa)3CheW: 513-640 aa (128 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
7-93 aa · 87 aa · 13.1% of protein
Raw tokenHpt:7:8.68e-16:93:87:84
2 H-kinase_dim#2
263-324 aa · 62 aa · 9.4% of protein
Raw tokenH-kinase_dim:263:1.35e-18:324:66:67
3 HATPase_c#3
371-508 aa · 138 aa · 20.8% of protein
Raw tokenHATPase_c:371:8.36e-17:508:138:109
4 CheW#4
513-640 aa · 128 aa · 19.3% of protein
Raw tokenCheW:513:5.38e-30:640:134:138
  • Raw architecture: Hpt:7:8.68e-16:93:87:84#H-kinase_dim:263:1.35e-18:324:66:67#HATPase_c:371:8.36e-17:508:138:109#CheW:513:5.38e-30:640:134:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_027688815::NZ_JAQCOE010000031.1::G00025
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span38687-40675Genomic interval covered by the local TCS group.
Context group IDGCF_027688815::NZ_JAQCOE010000031.1::G00025
Context members
PG027_RS14250
Partner locus tags
PG027_RS14250
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_270589834.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagPG027_RS14250Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JAQCOE010000031.1Sequence record reported by the local genomic context database.
Genomic interval38 687-40 675 nt1 989 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span38 687-40 675 ntGCF_027688815::NZ_JAQCOE010000031.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_027688815::NZ_JAQCOE010000031.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAQCOE010000031.1All displayed genes belong to this local TCS context.
Neighborhood span38 687-40 675 nt1 989 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
38 687 nt40 675 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0868779Run 6 · HK · 11857 sequences
Representative sequenceGCF_027688815#PG027_RS14250The current gene is the representative for this cluster.
PFAM architectureHpt + CheY-binding + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0868779

Simplified PFAM architecture for HKOC_0868779

PFAM domain coverage: 484 / 662 aa (73.1%)

1 aa662 aa
Hpt: 8-100 aaHptCheY-binding: 161-223 aaCheY-bindingH-kinase_dim: 261-324 aaH-kinase_dimHATPase_c: 372-508 aaHATPase_cCheW: 514-640 aaCheW
HptCheY-bindingH-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + CheY-binding + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[8-100] | CheY-binding[161-223] | H-kinase_dim[261-324] | HATPase_c[372-508] | CheW[514-640]
  • Domain count: 5
  • Matched identifier: HKOC_0868779
  • Positioned domains: Hpt 8-100 ; CheY-binding 161-223 ; H-kinase_dim 261-324 ; HATPase_c 372-508 ; CheW 514-640
Cluster members and taxonomy
Visualization

Representative gene: GCF_027688815#PG027_RS14250

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 562 · GCF_027688815
AssemblyASM2768881v1 · Scaffoldhaploid
Genome composition4 722 508 bp · 50,5% GCEscherichia coli
Signal transduction countsGenes 66 · HK 32 · RR 34CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key