1 HAMP#1
289-358 aa · 70 aa · 11.8% of protein
Raw token
HAMP:289:0.00000000269:358:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
O8D18_RS12385
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_027495705
ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_027495705#O8D18_RS12385Stable P2CS identifier used across views.
GenomeGCF_027495705Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 591 aa (42.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
Domain-by-domain annotation3 items
2 His_kinase#2
380-459 aa · 80 aa · 13.5% of protein
Raw token
His_kinase:380:8.18e-29:459:80:803 HATPase_c#3
485-585 aa · 101 aa · 17.1% of protein
Raw token
HATPase_c:485:0.000000789:585:101:109- Raw architecture: HAMP:289:0.00000000269:358:70:69#His_kinase:380:8.18e-29:459:80:80#HATPase_c:485:0.000000789:585:101:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_027495705::NZ_JAPZED010000015.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9590-12992Genomic interval covered by the local TCS group.
Identifiers
Old locus tagO8D18_12385RefSeq proteinWP_101872488.1
Context group ID
GCF_027495705::NZ_JAPZED010000015.1::G00038Context members
O8D18_RS12380O8D18_RS12385
Partner locus tags
O8D18_RS12380O8D18_RS12385
Partner old locus tags
O8D18_12380O8D18_12385
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_101872488.1Primary protein accession used for annex mappings.
UniProt accessionA0A2N5NVH5Primary UniProt accession resolved in the annex database.
UniProt IDA0A2N5NVH5_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagO8D18_RS12385Primary locus identifier stored in the genes table.
Old locus tagO8D18_12385Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAPZED010000015.1Sequence record reported by the local genomic context database.
Genomic interval11 217-12 992 nt1 776 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span9 590-12 992 ntGCF_027495705::NZ_JAPZED010000015.1::G00038
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_027495705::NZ_JAPZED010000015.1::G00038Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAPZED010000015.1All displayed genes belong to this local TCS context.
Neighborhood span9 590-12 992 nt3 403 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 590 nt12 992 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
O8D18_RS12380GCF_027495705#O8D18_RS12380
RRunclassified
9 590-11 212 nt · Reverse (-)
O8D18_RS12385GCF_027495705#O8D18_RS12385
HKClassicCurrent focus
11 217-12 992 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002865355#CDL25_RS15575Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase1 domain in the representative PFAM annotation.
PFAM architecture for HKOC_1106211
Simplified PFAM architecture for HKOC_1106211
PFAM domain coverage: 80 / 591 aa (13.5%)
1 aa591 aa
His_kinase
- Simplified architecture: His_kinase
- Raw architecture: His_kinase[380-459]
- Domain count: 1
- Matched identifier: HKOC_1106211
- Positioned domains: His_kinase 380-459
Cluster members and taxonomy
Representative gene: GCF_002865355#CDL25_RS15575
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_027495705
AssemblyASM2749570v1 · Contighaploid
Genome composition3 147 935 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 90 · HK 44 · RR 45CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key