Gene detail

CDL25_RS15575

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_002865355

ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002865355#CDL25_RS15575Stable P2CS identifier used across views.
GenomeGCF_002865355Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1106211Run 6 · 15 sequences · id 100% · cov 80% · representative
External referencesWP_101872488.1 · A0A2N5NVH5 · MIST4 CDL25_RS15575RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 591 aa (42.5%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
HAMP: 289-358 aa (70 aa)1His_kinase: 380-459 aa (80 aa)2HATPase_c: 485-585 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
289-358 aa · 70 aa · 11.8% of protein
Raw tokenHAMP:289:0.00000000269:358:70:69
2 His_kinase#2
380-459 aa · 80 aa · 13.5% of protein
Raw tokenHis_kinase:380:8.18e-29:459:80:80
3 HATPase_c#3
485-585 aa · 101 aa · 17.1% of protein
Raw tokenHATPase_c:485:0.000000789:585:101:109
  • Raw architecture: HAMP:289:0.00000000269:358:70:69#His_kinase:380:8.18e-29:459:80:80#HATPase_c:485:0.000000789:585:101:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002865355::NZ_NIHR01000048.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1132-4534Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDL25_15530RefSeq proteinWP_101872488.1
Context group IDGCF_002865355::NZ_NIHR01000048.1::G00035
Context members
CDL25_RS15575CDL25_RS15580
Partner locus tags
CDL25_RS15575CDL25_RS15580
Partner old locus tags
CDL25_15530CDL25_15535
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_101872488.1Primary protein accession used for annex mappings.
UniProt accessionA0A2N5NVH5Primary UniProt accession resolved in the annex database.
UniProt IDA0A2N5NVH5_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDL25_RS15575Primary locus identifier stored in the genes table.
Old locus tagCDL25_15530Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_NIHR01000048.1Sequence record reported by the local genomic context database.
Genomic interval1 132-2 907 nt1 776 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 132-4 534 ntGCF_002865355::NZ_NIHR01000048.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002865355::NZ_NIHR01000048.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_NIHR01000048.1All displayed genes belong to this local TCS context.
Neighborhood span1 132-4 534 nt3 403 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 132 nt4 534 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDL25_RS15575GCF_002865355#CDL25_RS15575
HKClassicCurrent focus

1 132-2 907 nt · Forward (+)

Old locus CDL25_15530RefSeq WP_101872488.1
CDL25_RS15580GCF_002865355#CDL25_RS15580
RRunclassified

2 912-4 534 nt · Forward (+)

Old locus CDL25_15535RefSeq WP_101872489.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1106211Run 6 · HK · 15 sequences
Representative sequenceGCF_002865355#CDL25_RS15575The current gene is the representative for this cluster.
PFAM architectureHis_kinase1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_1106211

Simplified PFAM architecture for HKOC_1106211

PFAM domain coverage: 80 / 591 aa (13.5%)

1 aa591 aa
His_kinase: 380-459 aaHis_kinase
His_kinase
  • Simplified architecture: His_kinase
  • Raw architecture: His_kinase[380-459]
  • Domain count: 1
  • Matched identifier: HKOC_1106211
  • Positioned domains: His_kinase 380-459
Cluster members and taxonomy
Visualization

Representative gene: GCF_002865355#CDL25_RS15575

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_002865355
AssemblyASM286535v1 · Scaffoldhaploid
Genome composition3 415 781 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 83 · HK 39 · RR 43CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key