Gene detail

J4G22_RS00880

Histidine kinase, Classic

Clostridioides difficile · GCF_025532335

ClassHKTypeClassicLength259 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_025532335#J4G22_RS00880Stable P2CS identifier used across views.
GenomeGCF_025532335Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2914533Run 6 · 22 sequences · id 100% · cov 80%
External referencesWP_021421323.1 · MIST4 J4G22_RS00880RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length259 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 259 aa (61.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for J4G22_RS00880
Domain-by-domain annotation2 items
1 HisKA#1
48-106 aa · 59 aa · 22.8% of protein
Raw tokenHisKA:48:0.0000000000000398:106:59:64
2 HATPase_c#2
159-257 aa · 99 aa · 38.2% of protein
Raw tokenHATPase_c:159:3.76e-19:257:100:109
  • Raw architecture: HisKA:48:0.0000000000000398:106:59:64#HATPase_c:159:3.76e-19:257:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_025532335::NZ_JAGDLY010000004.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span34788-36631Genomic interval covered by the local TCS group.
Identifiers
Old locus tagJ4G22_00875RefSeq proteinWP_021421323.1
Context group IDGCF_025532335::NZ_JAGDLY010000004.1::G00003
Context members
J4G22_RS00870J4G22_RS00880
Partner locus tags
J4G22_RS00870J4G22_RS00880
Partner old locus tags
J4G22_00870J4G22_00875
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021421323.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagJ4G22_RS00880Primary locus identifier stored in the genes table.
Old locus tagJ4G22_00875Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAGDLY010000004.1Sequence record reported by the local genomic context database.
Genomic interval35 852-36 631 nt780 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span34 788-36 631 ntGCF_025532335::NZ_JAGDLY010000004.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_025532335::NZ_JAGDLY010000004.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGDLY010000004.1All displayed genes belong to this local TCS context.
Neighborhood span34 788-36 631 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
34 788 nt36 631 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

J4G22_RS00870GCF_025532335#J4G22_RS00870
RROmpR

34 788-35 450 nt · Forward (+)

Old locus J4G22_00870RefSeq WP_021363239.1
J4G22_RS00880GCF_025532335#J4G22_RS00880
HKClassicCurrent focus

35 852-36 631 nt · Forward (+)

Old locus J4G22_00875RefSeq WP_021421323.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2914533Run 6 · HK · 22 sequences
Representative sequenceGCF_000451745#QSK_RS02260Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2914533

Simplified PFAM architecture for HKOC_2914533

PFAM domain coverage: 162 / 259 aa (62.5%)

1 aa259 aa
HisKA: 45-106 aaHisKAHATPase_c: 158-257 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[45-106] | HATPase_c[158-257]
  • Domain count: 2
  • Matched identifier: HKOC_2914533
  • Positioned domains: HisKA 45-106 ; HATPase_c 158-257
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451745#QSK_RS02260

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_025532335
AssemblyASM2553233v1 · Scaffoldhaploid
Genome composition4 417 807 bp · 29,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 49 · RR 56CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key