Gene detail

QSK_RS02260

Histidine kinase, Classic

Clostridioides difficile P29 · GCF_000451745

ClassHKTypeClassicLength259 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000451745#QSK_RS02260Stable P2CS identifier used across views.
GenomeGCF_000451745Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2914533Run 6 · 22 sequences · id 100% · cov 80% · representative
External referencesWP_021421323.1 · MIST4 QSK_RS02260RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length259 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 259 aa (61.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QSK_RS02260
Domain-by-domain annotation2 items
1 HisKA#1
48-106 aa · 59 aa · 22.8% of protein
Raw tokenHisKA:48:0.0000000000000398:106:59:64
2 HATPase_c#2
159-257 aa · 99 aa · 38.2% of protein
Raw tokenHATPase_c:159:3.76e-19:257:100:109
  • Raw architecture: HisKA:48:0.0000000000000398:106:59:64#HATPase_c:159:3.76e-19:257:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000451745::NZ_AVMD01000013.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span96768-98611Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQSK_0450RefSeq proteinWP_021421323.1
Context group IDGCF_000451745::NZ_AVMD01000013.1::G00005
Context members
QSK_RS02260QSK_RS02265
Partner locus tags
QSK_RS02260QSK_RS02265
Partner old locus tags
QSK_0450QSK_0452
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021421323.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQSK_RS02260Primary locus identifier stored in the genes table.
Old locus tagQSK_0450Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVMD01000013.1Sequence record reported by the local genomic context database.
Genomic interval96 768-97 547 nt780 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span96 768-98 611 ntGCF_000451745::NZ_AVMD01000013.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000451745::NZ_AVMD01000013.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVMD01000013.1All displayed genes belong to this local TCS context.
Neighborhood span96 768-98 611 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
96 768 nt98 611 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QSK_RS02260GCF_000451745#QSK_RS02260
HKClassicCurrent focus

96 768-97 547 nt · Reverse (-)

Old locus QSK_0450RefSeq WP_021421323.1
QSK_RS02265GCF_000451745#QSK_RS02265
RROmpR

97 949-98 611 nt · Reverse (-)

Old locus QSK_0452RefSeq WP_021363239.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2914533Run 6 · HK · 22 sequences
Representative sequenceGCF_000451745#QSK_RS02260The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2914533

Simplified PFAM architecture for HKOC_2914533

PFAM domain coverage: 162 / 259 aa (62.5%)

1 aa259 aa
HisKA: 45-106 aaHisKAHATPase_c: 158-257 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[45-106] | HATPase_c[158-257]
  • Domain count: 2
  • Matched identifier: HKOC_2914533
  • Positioned domains: HisKA 45-106 ; HATPase_c 158-257
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451745#QSK_RS02260

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 411 · GCF_000451745
AssemblyASM45174v2 · Contighaploid
Genome composition4 156 041 bp · 29,0% GCClostridioides difficile P29
Signal transduction countsGenes 101 · HK 49 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key