1 HAMP#1
164-232 aa · 69 aa · 15.0% of protein
Raw token
HAMP:164:0.00000137:232:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
A7A21_RS16655
Histidine kinase, Classic
Escherichia coli · GCF_024584825
ClassHKTypeClassicLength461 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024584825#A7A21_RS16655Stable P2CS identifier used across views.
GenomeGCF_024584825Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length461 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 461 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa461 aa
Domain-by-domain annotation3 items
2 HisKA#2
238-301 aa · 64 aa · 13.9% of protein
Raw token
HisKA:238:0.000000000025:301:64:643 HATPase_c#3
348-453 aa · 106 aa · 23.0% of protein
Raw token
HATPase_c:348:6.13e-26:453:110:109- Raw architecture: HAMP:164:0.00000137:232:70:69#HisKA:238:0.000000000025:301:64:64#HATPase_c:348:6.13e-26:453:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024584825::NZ_CP076276.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3396026-3398067Genomic interval covered by the local TCS group.
Identifiers
Old locus tagA7A21_16600RefSeq proteinWP_257114295.1
Context group ID
GCF_024584825::NZ_CP076276.1::G00027Context members
A7A21_RS16650A7A21_RS16655
Partner locus tags
A7A21_RS16650A7A21_RS16655
Partner old locus tags
A7A21_16595A7A21_16600
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_257114295.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagA7A21_RS16655Primary locus identifier stored in the genes table.
Old locus tagA7A21_16600Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP076276.1Sequence record reported by the local genomic context database.
Genomic interval3 396 682-3 398 067 nt1 386 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 396 026-3 398 067 ntGCF_024584825::NZ_CP076276.1::G00027
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024584825::NZ_CP076276.1::G00027Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP076276.1All displayed genes belong to this local TCS context.
Neighborhood span3 396 026-3 398 067 nt2 042 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 396 026 nt3 398 067 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
A7A21_RS16650GCF_024584825#A7A21_RS16650
RROmpR
3 396 026-3 396 685 nt · Forward (+)
A7A21_RS16655GCF_024584825#A7A21_RS16655
HKClassicCurrent focus
3 396 682-3 398 067 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024584825#A7A21_RS16655The current gene is the representative for this cluster.
PFAM architecture2CSK_N + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1827905
Simplified PFAM architecture for HKOC_1827905
PFAM domain coverage: 299 / 461 aa (64.9%)
1 aa461 aa
2CSK_NHisKAHATPase_c
- Simplified architecture: 2CSK_N + HisKA + HATPase_c
- Raw architecture: 2CSK_N[23-157] | HisKA[237-301] | HATPase_c[349-447]
- Domain count: 3
- Matched identifier: HKOC_1827905
- Positioned domains: 2CSK_N 23-157 ; HisKA 237-301 ; HATPase_c 349-447
Cluster members and taxonomy
Representative gene: GCF_024584825#A7A21_RS16655
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 562 · GCF_024584825
AssemblyASM2458482v1 · Complete Genomehaploid
Genome composition5 125 428 bp · 50,5% GCEscherichia coli
Signal transduction countsGenes 61 · HK 30 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key