Gene detail

NE621_RS07975

Histidine kinase, Classic

Agathobacter rectalis · GCF_024461635

ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024461635#NE621_RS07975Stable P2CS identifier used across views.
GenomeGCF_024461635Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Agathobacter
Selected clusterHKOC_1114829Run 6 · 20 sequences · id 100% · cov 80%
External referencesWP_022292570.1 · A0A173R808 · MIST4 NE621_RS07975RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage255 / 589 aa (43.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa589 aa
HAMP: 294-365 aa (72 aa)1His_kinase: 384-462 aa (79 aa)2HATPase_c: 479-582 aa (104 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
294-365 aa · 72 aa · 12.2% of protein
Raw tokenHAMP:294:0.00000000607:365:72:69
2 His_kinase#2
384-462 aa · 79 aa · 13.4% of protein
Raw tokenHis_kinase:384:2.33e-31:462:80:80
3 HATPase_c#3
479-582 aa · 104 aa · 17.7% of protein
Raw tokenHATPase_c:479:0.00000000000000151:582:112:109
  • Raw architecture: HAMP:294:0.00000000607:365:72:69#His_kinase:384:2.33e-31:462:80:80#HATPase_c:479:0.00000000000000151:582:112:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024461635::NZ_JANFZZ010000008.1::G00049
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span123016-126280Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE621_07995RefSeq proteinWP_022292570.1
Context group IDGCF_024461635::NZ_JANFZZ010000008.1::G00049
Context members
NE621_RS07970NE621_RS07975
Partner locus tags
NE621_RS07970NE621_RS07975
Partner old locus tags
NE621_07990NE621_07995
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022292570.1Primary protein accession used for annex mappings.
UniProt accessionA0A173R808Primary UniProt accession resolved in the annex database.
UniProt IDA0A173R808_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE621_RS07975Primary locus identifier stored in the genes table.
Old locus tagNE621_07995Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZZ010000008.1Sequence record reported by the local genomic context database.
Genomic interval124 511-126 280 nt1 770 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span123 016-126 280 ntGCF_024461635::NZ_JANFZZ010000008.1::G00049

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024461635::NZ_JANFZZ010000008.1::G00049

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZZ010000008.1All displayed genes belong to this local TCS context.
Neighborhood span123 016-126 280 nt3 265 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
123 016 nt126 280 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE621_RS07970GCF_024461635#NE621_RS07970
RRunclassified

123 016-124 518 nt · Reverse (-)

Old locus NE621_07990RefSeq WP_306780772.1
NE621_RS07975GCF_024461635#NE621_RS07975
HKClassicCurrent focus

124 511-126 280 nt · Reverse (-)

Old locus NE621_07995RefSeq WP_022292570.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1114829Run 6 · HK · 20 sequences
Representative sequenceGCF_000209955#ERE_RS04610Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1114829

Simplified PFAM architecture for HKOC_1114829

PFAM domain coverage: 230 / 589 aa (39.0%)

1 aa589 aa
HAMP: 318-366 aaHAMPHis_kinase: 385-462 aaHis_kinaseHATPase_c: 479-581 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[318-366] | His_kinase[385-462] | HATPase_c[479-581]
  • Domain count: 3
  • Matched identifier: HKOC_1114829
  • Positioned domains: HAMP 318-366 ; His_kinase 385-462 ; HATPase_c 479-581
Cluster members and taxonomy
Visualization

Representative gene: GCF_000209955#ERE_RS04610

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 491 · GCF_024461635
AssemblyASM2446163v1 · Contighaploid
Genome composition3 406 890 bp · 41,0% GCAgathobacter rectalis
Signal transduction countsGenes 92 · HK 37 · RR 52CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAgathobacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Agathobacter

Related genes

Preview from the same derived genome key