Gene detail

NE621_RS03435

Histidine kinase, Classic

Agathobacter rectalis · GCF_024461635

ClassHKTypeClassicLength476 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024461635#NE621_RS03435Stable P2CS identifier used across views.
GenomeGCF_024461635Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Agathobacter
Selected clusterHKOC_1659619Run 6 · 4 sequences · id 100% · cov 80%
External referencesWP_306780401.1 · A0AAW4U5C7 · MIST4 NE621_RS03435RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length476 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 476 aa (49.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa476 aa
HAMP: 175-241 aa (67 aa)1HisKA: 253-313 aa (61 aa)2HATPase_c: 364-471 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
175-241 aa · 67 aa · 14.1% of protein
Raw tokenHAMP:175:6.19e-16:241:67:69
2 HisKA#2
253-313 aa · 61 aa · 12.8% of protein
Raw tokenHisKA:253:0.00000000118:313:61:64
3 HATPase_c#3
364-471 aa · 108 aa · 22.7% of protein
Raw tokenHATPase_c:364:6.84e-28:471:109:109
  • Raw architecture: HAMP:175:6.19e-16:241:67:69#HisKA:253:0.00000000118:313:61:64#HATPase_c:364:6.84e-28:471:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_024461635::NZ_JANFZZ010000003.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span48052-50141Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNE621_03440RefSeq proteinWP_306780401.1
Context group IDGCF_024461635::NZ_JANFZZ010000003.1::G00029
Context members
NE621_RS03430NE621_RS03435
Partner locus tags
NE621_RS03430NE621_RS03435
Partner old locus tags
NE621_03435NE621_03440
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_306780401.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW4U5C7Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW4U5C7_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagNE621_RS03435Primary locus identifier stored in the genes table.
Old locus tagNE621_03440Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANFZZ010000003.1Sequence record reported by the local genomic context database.
Genomic interval48 711-50 141 nt1 431 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span48 052-50 141 ntGCF_024461635::NZ_JANFZZ010000003.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_024461635::NZ_JANFZZ010000003.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANFZZ010000003.1All displayed genes belong to this local TCS context.
Neighborhood span48 052-50 141 nt2 090 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
48 052 nt50 141 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

NE621_RS03430GCF_024461635#NE621_RS03430
RROmpR

48 052-48 714 nt · Forward (+)

Old locus NE621_03435RefSeq WP_015569484.1
NE621_RS03435GCF_024461635#NE621_RS03435
HKClassicCurrent focus

48 711-50 141 nt · Forward (+)

Old locus NE621_03440RefSeq WP_306780401.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1659619Run 6 · HK · 4 sequences
Representative sequenceGCF_020557395#LIZ56_RS00905Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1659619

Simplified PFAM architecture for HKOC_1659619

PFAM domain coverage: 218 / 476 aa (45.8%)

1 aa476 aa
HAMP: 191-241 aaHAMPHisKA: 254-314 aaHisKAHATPase_c: 365-470 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[191-241] | HisKA[254-314] | HATPase_c[365-470]
  • Domain count: 3
  • Matched identifier: HKOC_1659619
  • Positioned domains: HAMP 191-241 ; HisKA 254-314 ; HATPase_c 365-470
Cluster members and taxonomy
Visualization

Representative gene: GCF_020557395#LIZ56_RS00905

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 39 491 · GCF_024461635
AssemblyASM2446163v1 · Contighaploid
Genome composition3 406 890 bp · 41,0% GCAgathobacter rectalis
Signal transduction countsGenes 92 · HK 37 · RR 52CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAgathobacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Agathobacter

Related genes

Preview from the same derived genome key