1 HAMP#1
170-237 aa · 68 aa · 14.7% of protein
Raw token
HAMP:170:0.0000000000016:237:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NMF94_RS16545
Histidine kinase, Classic
Clostridioides difficile · GCF_024260185
ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024260185#NMF94_RS16545Stable P2CS identifier used across views.
GenomeGCF_024260185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 464 aa (45.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
249-308 aa · 60 aa · 12.9% of protein
Raw token
HisKA:249:0.000000000418:308:61:643 HATPase_c#3
355-439 aa · 85 aa · 18.3% of protein
Raw token
HATPase_c:355:0.00000000000000842:439:88:109- Raw architecture: HAMP:170:0.0000000000016:237:68:69#HisKA:249:0.000000000418:308:61:64#HATPase_c:355:0.00000000000000842:439:88:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024260185::NZ_JANCKS010000032.1::G00031
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span33034-35068Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF94_16545RefSeq proteinWP_021407747.1
Context group ID
GCF_024260185::NZ_JANCKS010000032.1::G00031Context members
NMF94_RS16540NMF94_RS16545
Partner locus tags
NMF94_RS16540NMF94_RS16545
Partner old locus tags
NMF94_16540NMF94_16545
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021407747.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNMF94_RS16545Primary locus identifier stored in the genes table.
Old locus tagNMF94_16545Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCKS010000032.1Sequence record reported by the local genomic context database.
Genomic interval33 674-35 068 nt1 395 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span33 034-35 068 ntGCF_024260185::NZ_JANCKS010000032.1::G00031
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024260185::NZ_JANCKS010000032.1::G00031Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCKS010000032.1All displayed genes belong to this local TCS context.
Neighborhood span33 034-35 068 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
33 034 nt35 068 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NMF94_RS16540GCF_024260185#NMF94_RS16540
RROmpR
33 034-33 681 nt · Forward (+)
NMF94_RS16545GCF_024260185#NMF94_RS16545
HKClassicCurrent focus
33 674-35 068 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000450785#QO7_RS02445Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1784204
Simplified PFAM architecture for HKOC_1784204
PFAM domain coverage: 145 / 464 aa (31.3%)
1 aa464 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[250-308] | HATPase_c[355-440]
- Domain count: 2
- Matched identifier: HKOC_1784204
- Positioned domains: HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Representative gene: GCF_000450785#QO7_RS02445
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_024260185
AssemblyASM2426018v1 · Contighaploid
Genome composition4 088 797 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key