1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw token
HisKA:309:0.0000000000000163:375:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NMF94_RS00065
Histidine kinase, Classic
Clostridioides difficile · GCF_024260185
ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024260185#NMF94_RS00065Stable P2CS identifier used across views.
GenomeGCF_024260185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw token
HATPase_c:428:0.0000000428:513:90:109- Raw architecture: HisKA:309:0.0000000000000163:375:67:64#HATPase_c:428:0.0000000428:513:90:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024260185::NZ_JANCKS010000001.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span7961-10238Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF94_00065RefSeq proteinWP_168347010.1
Context group ID
GCF_024260185::NZ_JANCKS010000001.1::G00012Context members
NMF94_RS00060NMF94_RS00065
Partner locus tags
NMF94_RS00060NMF94_RS00065
Partner old locus tags
NMF94_00060NMF94_00065
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_168347010.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNMF94_RS00065Primary locus identifier stored in the genes table.
Old locus tagNMF94_00065Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCKS010000001.1Sequence record reported by the local genomic context database.
Genomic interval8 646-10 238 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span7 961-10 238 ntGCF_024260185::NZ_JANCKS010000001.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024260185::NZ_JANCKS010000001.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCKS010000001.1All displayed genes belong to this local TCS context.
Neighborhood span7 961-10 238 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 961 nt10 238 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NMF94_RS00060GCF_024260185#NMF94_RS00060
RROmpR
7 961-8 677 nt · Forward (+)
NMF94_RS00065GCF_024260185#NMF94_RS00065
HKClassicCurrent focus
8 646-10 238 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_012276945#GSQ50_RS06815Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1357030
Simplified PFAM architecture for HKOC_1357030
PFAM domain coverage: 191 / 530 aa (36.0%)
1 aa530 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
- Domain count: 3
- Matched identifier: HKOC_1357030
- Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Representative gene: GCF_012276945#GSQ50_RS06815
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_024260185
AssemblyASM2426018v1 · Contighaploid
Genome composition4 088 797 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key