1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw token
HisKA:196:0.000000000017:260:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
NMF99_RS12520
Histidine kinase, Classic
Clostridioides difficile · GCF_024259965
ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_024259965#NMF99_RS12520Stable P2CS identifier used across views.
GenomeGCF_024259965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa425 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw token
HATPase_c:307:4.13e-19:424:119:109- Raw architecture: HisKA:196:0.000000000017:260:65:64#HATPase_c:307:4.13e-19:424:119:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_024259965::NZ_JANCLH010000045.1::G00024
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span23874-25803Genomic interval covered by the local TCS group.
Identifiers
Old locus tagNMF99_12515RefSeq proteinWP_074073338.1
Context group ID
GCF_024259965::NZ_JANCLH010000045.1::G00024Context members
NMF99_RS12520NMF99_RS12525
Partner locus tags
NMF99_RS12520NMF99_RS12525
Partner old locus tags
NMF99_12515NMF99_12520
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_074073338.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagNMF99_RS12520Primary locus identifier stored in the genes table.
Old locus tagNMF99_12515Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JANCLH010000045.1Sequence record reported by the local genomic context database.
Genomic interval23 874-25 151 nt1 278 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span23 874-25 803 ntGCF_024259965::NZ_JANCLH010000045.1::G00024
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_024259965::NZ_JANCLH010000045.1::G00024Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JANCLH010000045.1All displayed genes belong to this local TCS context.
Neighborhood span23 874-25 803 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
23 874 nt25 803 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
NMF99_RS12520GCF_024259965#NMF99_RS12520
HKClassicCurrent focus
23 874-25 151 nt · Reverse (-)
NMF99_RS12525GCF_024259965#NMF99_RS12525
RROmpR
25 135-25 803 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_024259965#NMF99_RS12520The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2220062
Simplified PFAM architecture for HKOC_2220062
PFAM domain coverage: 179 / 425 aa (42.1%)
1 aa425 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[197-260] | HATPase_c[308-422]
- Domain count: 2
- Matched identifier: HKOC_2220062
- Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Representative gene: GCF_024259965#NMF99_RS12520
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_024259965
AssemblyASM2425996v1 · Contighaploid
Genome composition4 076 492 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 52CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key