1 Response_reg#1
3-111 aa · 109 aa · 48.9% of protein
Raw token
Response_reg:3:6.24e-30:111:109:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HZT08_RS13520
Response regulator OmpR family
Shigella flexneri · GCF_022494435
ClassRRTypeOmpRLength223 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_022494435#HZT08_RS13520Stable P2CS identifier used across views.
GenomeGCF_022494435Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length223 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage185 / 223 aa (83.0%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa223 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
145-220 aa · 76 aa · 34.1% of protein
Raw token
Trans_reg_C:145:6.86e-22:220:77:77- Raw architecture: Response_reg:3:6.24e-30:111:109:111#Trans_reg_C:145:6.86e-22:220:77:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_022494435::NZ_CP058790.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2768695-2770826Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHZT08_13395RefSeq proteinWP_001265481.1
Context group ID
GCF_022494435::NZ_CP058790.1::G00023Context members
HZT08_RS13520HZT08_RS13525
Partner locus tags
HZT08_RS13520HZT08_RS13525
Partner old locus tags
HZT08_13395HZT08_13400
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001265481.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0FKU4Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0FKU4_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHZT08_RS13520Primary locus identifier stored in the genes table.
Old locus tagHZT08_13395Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP058790.1Sequence record reported by the local genomic context database.
Genomic interval2 768 695-2 769 366 nt672 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 768 695-2 770 826 ntGCF_022494435::NZ_CP058790.1::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_022494435::NZ_CP058790.1::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP058790.1All displayed genes belong to this local TCS context.
Neighborhood span2 768 695-2 770 826 nt2 132 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 768 695 nt2 770 826 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HZT08_RS13520GCF_022494435#HZT08_RS13520
RROmpRCurrent focus
2 768 695-2 769 366 nt · Forward (+)
HZT08_RS13525GCF_022494435#HZT08_RS13525
HKClassic
2 769 366-2 770 826 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_021547115#L1015_RS00145Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1558688
Simplified PFAM architecture for RROC_1558688
PFAM domain coverage: 185 / 224 aa (82.6%)
1 aa224 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[3-112] | Trans_reg_C[146-220]
- Domain count: 2
- Matched identifier: RROC_1558688
- Positioned domains: Response_reg 3-112 ; Trans_reg_C 146-220
Cluster members and taxonomy
Representative gene: GCF_021547115#L1015_RS00145
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 623 · GCF_022494435
AssemblyASM2249443v1 · Complete Genomehaploid
Genome composition4 998 483 bp · 50,5% GCShigella flexneri
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusShigella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Shigella
Related genes
Preview from the same derived genome key