Gene detail

LWF07_RS12490

Histidine kinase, Classic

Clostridioides difficile · GCF_021284495

ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284495#LWF07_RS12490Stable P2CS identifier used across views.
GenomeGCF_021284495Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2118634Run 6 · 68 sequences · id 100% · cov 80%
External referencesWP_016728679.1 · MIST4 LWF07_RS12490RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa417 aa
HisKA: 199-258 aa (60 aa)1HATPase_c: 304-410 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw tokenHisKA:199:0.0000000013:258:60:64
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw tokenHATPase_c:304:2.08e-21:410:107:109
  • Raw architecture: HisKA:199:0.0000000013:258:60:64#HATPase_c:304:2.08e-21:410:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284495::NZ_JAJSNU010000227.1::G00057
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span792-2727Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWF07_12525RefSeq proteinWP_016728679.1
Context group IDGCF_021284495::NZ_JAJSNU010000227.1::G00057
Context members
LWF07_RS12485LWF07_RS12490
Partner locus tags
LWF07_RS12485LWF07_RS12490
Partner old locus tags
LWF07_12520LWF07_12525
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016728679.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWF07_RS12490Primary locus identifier stored in the genes table.
Old locus tagLWF07_12525Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNU010000227.1Sequence record reported by the local genomic context database.
Genomic interval1 474-2 727 nt1 254 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span792-2 727 ntGCF_021284495::NZ_JAJSNU010000227.1::G00057

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284495::NZ_JAJSNU010000227.1::G00057

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNU010000227.1All displayed genes belong to this local TCS context.
Neighborhood span792-2 727 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
792 nt2 727 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWF07_RS12485GCF_021284495#LWF07_RS12485
RROmpR

792-1 496 nt · Forward (+)

Old locus LWF07_12520RefSeq WP_011861224.1
LWF07_RS12490GCF_021284495#LWF07_RS12490
HKClassicCurrent focus

1 474-2 727 nt · Forward (+)

Old locus LWF07_12525RefSeq WP_016728679.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2118634Run 6 · HK · 68 sequences
Representative sequenceGCF_033840485#SIK40_RS09890Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2118634

Simplified PFAM architecture for HKOC_2118634

PFAM domain coverage: 169 / 436 aa (38.8%)

1 aa436 aa
HisKA: 196-258 aaHisKAHATPase_c: 305-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[196-258] | HATPase_c[305-410]
  • Domain count: 2
  • Matched identifier: HKOC_2118634
  • Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_033840485#SIK40_RS09890

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284495
AssemblyASM2128449v1 · Contighaploid
Genome composition4 098 148 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 108 · HK 51 · RR 56CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key