Gene detail

LWE75_RS08835

Histidine kinase, Classic

Clostridioides difficile · GCF_021284485

ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284485#LWE75_RS08835Stable P2CS identifier used across views.
GenomeGCF_021284485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2882042Run 6 · 98 sequences · id 100% · cov 80%
External referencesWP_016729487.1 · MIST4 LWE75_RS08835RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 305 aa (56.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for LWE75_RS08835
Domain-by-domain annotation2 items
1 HisKA#1
87-150 aa · 64 aa · 21.0% of protein
Raw tokenHisKA:87:0.0000000518:150:64:64
2 HATPase_c#2
197-304 aa · 108 aa · 35.4% of protein
Raw tokenHATPase_c:197:2.4e-27:304:108:109
  • Raw architecture: HisKA:87:0.0000000518:150:64:64#HATPase_c:197:2.4e-27:304:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284485::NZ_JAJSNR010000152.1::G00047
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1090-2708Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE75_08825RefSeq proteinWP_016729487.1
Context group IDGCF_021284485::NZ_JAJSNR010000152.1::G00047
Context members
LWE75_RS08830LWE75_RS08835
Partner locus tags
LWE75_RS08830LWE75_RS08835
Partner old locus tags
LWE75_08820LWE75_08825
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016729487.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE75_RS08835Primary locus identifier stored in the genes table.
Old locus tagLWE75_08825Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNR010000152.1Sequence record reported by the local genomic context database.
Genomic interval1 791-2 708 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 090-2 708 ntGCF_021284485::NZ_JAJSNR010000152.1::G00047

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284485::NZ_JAJSNR010000152.1::G00047

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNR010000152.1All displayed genes belong to this local TCS context.
Neighborhood span1 090-2 708 nt1 619 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 090 nt2 708 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE75_RS08830GCF_021284485#LWE75_RS08830
RROmpR

1 090-1 788 nt · Forward (+)

Old locus LWE75_08820RefSeq WP_002347245.1
LWE75_RS08835GCF_021284485#LWE75_RS08835
HKClassicCurrent focus

1 791-2 708 nt · Forward (+)

Old locus LWE75_08825RefSeq WP_016729487.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2882042Run 6 · HK · 98 sequences
Representative sequenceGCF_000242355#MUI_RS0116830Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2882042

Simplified PFAM architecture for HKOC_2882042

PFAM domain coverage: 171 / 305 aa (56.1%)

1 aa305 aa
HisKA: 87-150 aaHisKAHATPase_c: 197-303 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[87-150] | HATPase_c[197-303]
  • Domain count: 2
  • Matched identifier: HKOC_2882042
  • Positioned domains: HisKA 87-150 ; HATPase_c 197-303
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0116830

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284485
AssemblyASM2128448v1 · Contighaploid
Genome composition4 077 225 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key