1 HAMP#1
6-74 aa · 69 aa · 16.1% of protein
Raw token
HAMP:6:0.000000849:74:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE75_RS01975
Histidine kinase, Classic
Clostridioides difficile · GCF_021284485
ClassHKTypeClassicLength429 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284485#LWE75_RS01975Stable P2CS identifier used across views.
GenomeGCF_021284485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPPAS_9HisKAHATPase_c
Protein length429 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage340 / 429 aa (79.3%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation4 items
2 PAS_9#2
96-195 aa · 100 aa · 23.3% of protein
Raw token
PAS_9:96:0.00000124:195:103:1023 HisKA#3
202-268 aa · 67 aa · 15.6% of protein
Raw token
HisKA:202:3.14e-18:268:67:644 HATPase_c#4
319-422 aa · 104 aa · 24.2% of protein
Raw token
HATPase_c:319:3.66e-30:422:104:109- Raw architecture: HAMP:6:0.000000849:74:69:69#PAS_9:96:0.00000124:195:103:102#HisKA:202:3.14e-18:268:67:64#HATPase_c:319:3.66e-30:422:104:109
- Domain description: 1 HAMP,1 PAS_9,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_021284485::NZ_JAJSNR010000016.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span7727-9737Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE75_01975RefSeq proteinWP_016728477.1
Context group ID
GCF_021284485::NZ_JAJSNR010000016.1::G00022Context members
LWE75_RS01970LWE75_RS01975
Partner locus tags
LWE75_RS01970LWE75_RS01975
Partner old locus tags
LWE75_01970LWE75_01975
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_016728477.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE75_RS01975Primary locus identifier stored in the genes table.
Old locus tagLWE75_01975Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNR010000016.1Sequence record reported by the local genomic context database.
Genomic interval8 448-9 737 nt1 290 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span7 727-9 737 ntGCF_021284485::NZ_JAJSNR010000016.1::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021284485::NZ_JAJSNR010000016.1::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNR010000016.1All displayed genes belong to this local TCS context.
Neighborhood span7 727-9 737 nt2 011 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 727 nt9 737 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWE75_RS01970GCF_021284485#LWE75_RS01970
RROmpR
7 727-8 419 nt · Forward (+)
LWE75_RS01975GCF_021284485#LWE75_RS01975
HKClassicCurrent focus
8 448-9 737 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000242355#MUI_RS0100685Use this link to inspect the representative gene detail.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2180370
Simplified PFAM architecture for HKOC_2180370
PFAM domain coverage: 321 / 429 aa (74.8%)
1 aa429 aa
HAMPPASHisKAHATPase_c
- Simplified architecture: HAMP + PAS + HisKA + HATPase_c
- Raw architecture: HAMP[33-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
- Domain count: 4
- Matched identifier: HKOC_2180370
- Positioned domains: HAMP 33-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Representative gene: GCF_000242355#MUI_RS0100685
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284485
AssemblyASM2128448v1 · Contighaploid
Genome composition4 077 225 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key