1 HisKA#1
123-189 aa · 67 aa · 19.5% of protein
Raw token
HisKA:123:0.00000012:189:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE75_RS00265
Histidine kinase, Classic
Clostridioides difficile · GCF_021284485
ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284485#LWE75_RS00265Stable P2CS identifier used across views.
GenomeGCF_021284485Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 343 aa (49.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw token
HATPase_c:241:9.42e-28:341:101:109- Raw architecture: HisKA:123:0.00000012:189:67:64#HATPase_c:241:9.42e-28:341:101:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_021284485::NZ_JAJSNR010000001.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span45714-47434Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE75_00265RefSeq proteinWP_004611601.1
Context group ID
GCF_021284485::NZ_JAJSNR010000001.1::G00028Context members
LWE75_RS00260LWE75_RS00265
Partner locus tags
LWE75_RS00260LWE75_RS00265
Partner old locus tags
LWE75_00260LWE75_00265
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_004611601.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE75_RS00265Primary locus identifier stored in the genes table.
Old locus tagLWE75_00265Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNR010000001.1Sequence record reported by the local genomic context database.
Genomic interval46 403-47 434 nt1 032 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span45 714-47 434 ntGCF_021284485::NZ_JAJSNR010000001.1::G00028
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021284485::NZ_JAJSNR010000001.1::G00028Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNR010000001.1All displayed genes belong to this local TCS context.
Neighborhood span45 714-47 434 nt1 721 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
45 714 nt47 434 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWE75_RS00260GCF_021284485#LWE75_RS00260
RROmpR
45 714-46 406 nt · Forward (+)
LWE75_RS00265GCF_021284485#LWE75_RS00265
HKClassicCurrent focus
46 403-47 434 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_013299755#G4366_RS10215Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2829451
Simplified PFAM architecture for HKOC_2829451
PFAM domain coverage: 174 / 343 aa (50.7%)
1 aa343 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[124-189] | HATPase_c[235-342]
- Domain count: 2
- Matched identifier: HKOC_2829451
- Positioned domains: HisKA 124-189 ; HATPase_c 235-342
Cluster members and taxonomy
Representative gene: GCF_013299755#G4366_RS10215
Displayed with 5 columns and 10 rows per page from the local display config.
Showing members 1 to 12 over 12 total members. Page 1 / 1.
GCF_013299755#G4366_RS10215 (representative) | ||||
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284485
AssemblyASM2128448v1 · Contighaploid
Genome composition4 077 225 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key