Gene detail

LWE84_RS15620

Histidine kinase, Classic

Clostridioides difficile · GCF_021284455

ClassHKTypeClassicLength666 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284455#LWE84_RS15620Stable P2CS identifier used across views.
GenomeGCF_021284455Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0843923Run 6 · 7 sequences · id 100% · cov 80%
External referencesWP_232915374.1 · MIST4 LWE84_RS15620RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length666 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage386 / 666 aa (58.0%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa666 aa
SBP_bac_3: 60-280 aa (221 aa)1HisKA: 448-510 aa (63 aa)2HATPase_c: 559-660 aa (102 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
60-280 aa · 221 aa · 33.2% of protein
Raw tokenSBP_bac_3:60:1.72e-41:280:230:224
2 HisKA#2
448-510 aa · 63 aa · 9.5% of protein
Raw tokenHisKA:448:0.0000000000000431:510:63:64
3 HATPase_c#3
559-660 aa · 102 aa · 15.3% of protein
Raw tokenHATPase_c:559:2.5e-23:660:103:109
  • Raw architecture: SBP_bac_3:60:1.72e-41:280:230:224#HisKA:448:0.0000000000000431:510:63:64#HATPase_c:559:2.5e-23:660:103:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284455::NZ_JAJSNS010000384.1::G00060
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-3325Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE84_15625RefSeq proteinWP_232915374.1
Context group IDGCF_021284455::NZ_JAJSNS010000384.1::G00060
Context members
LWE84_RS15620LWE84_RS15625
Partner locus tags
LWE84_RS15620LWE84_RS15625
Partner old locus tags
LWE84_15625LWE84_15630
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_232915374.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE84_RS15620Primary locus identifier stored in the genes table.
Old locus tagLWE84_15625Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNS010000384.1Sequence record reported by the local genomic context database.
Genomic interval1-2 003 nt2 003 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-3 325 ntGCF_021284455::NZ_JAJSNS010000384.1::G00060

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284455::NZ_JAJSNS010000384.1::G00060

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNS010000384.1All displayed genes belong to this local TCS context.
Neighborhood span1-3 325 nt3 325 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt3 325 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE84_RS15625GCF_021284455#LWE84_RS15625
RRNtrC

2 003-3 325 nt · Forward (+)

Old locus LWE84_15630RefSeq WP_016728592.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0843923Run 6 · HK · 7 sequences
Representative sequenceGCF_021284575#LWE98_RS15750Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0843923

Simplified PFAM architecture for HKOC_0843923

PFAM domain coverage: 385 / 671 aa (57.4%)

1 aa671 aa
SBP_bac_3: 67-284 aaSBP_bac_3HisKA: 455-516 aaHisKAHATPase_c: 562-666 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[67-284] | HisKA[455-516] | HATPase_c[562-666]
  • Domain count: 3
  • Matched identifier: HKOC_0843923
  • Positioned domains: SBP_bac_3 67-284 ; HisKA 455-516 ; HATPase_c 562-666
Cluster members and taxonomy
Visualization

Representative gene: GCF_021284575#LWE98_RS15750

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284455
AssemblyASM2128445v1 · Contighaploid
Genome composition4 089 563 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key