Gene detail

LWF11_RS00155

Histidine kinase, Classic

Clostridioides difficile · GCF_021284275

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021284275#LWF11_RS00155Stable P2CS identifier used across views.
GenomeGCF_021284275Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674086Run 6 · 679 sequences · id 100% · cov 80%
External referencesWP_003434751.1 · Q188S3 · MIST4 LWF11_RS00155RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 161-238 aa (78 aa)1HisKA: 250-315 aa (66 aa)2HATPase_c: 365-471 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000139:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000206:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:2.74e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000139:238:78:69#HisKA:250:0.00000000206:315:66:64#HATPase_c:365:2.74e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021284275::NZ_JAJSNK010000002.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6374-8509Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWF11_00150RefSeq proteinWP_003434751.1
Context group IDGCF_021284275::NZ_JAJSNK010000002.1::G00042
Context members
LWF11_RS00155LWF11_RS00160
Partner locus tags
LWF11_RS00155LWF11_RS00160
Partner old locus tags
LWF11_00150LWF11_00155
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003434751.1Primary protein accession used for annex mappings.
UniProt accessionQ188S3Primary UniProt accession resolved in the annex database.
UniProt IDQ188S3_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWF11_RS00155Primary locus identifier stored in the genes table.
Old locus tagLWF11_00150Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNK010000002.1Sequence record reported by the local genomic context database.
Genomic interval6 374-7 798 nt1 425 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span6 374-8 509 ntGCF_021284275::NZ_JAJSNK010000002.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021284275::NZ_JAJSNK010000002.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNK010000002.1All displayed genes belong to this local TCS context.
Neighborhood span6 374-8 509 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 374 nt8 509 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWF11_RS00155GCF_021284275#LWF11_RS00155
HKClassicCurrent focus

6 374-7 798 nt · Reverse (-)

Old locus LWF11_00150RefSeq WP_003434751.1
LWF11_RS00160GCF_021284275#LWF11_RS00160
RROmpR

7 817-8 509 nt · Reverse (-)

Old locus LWF11_00155RefSeq WP_003434748.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674086Run 6 · HK · 679 sequences
Representative sequenceGCF_000009205#CD630_RS02960Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674086

Simplified PFAM architecture for HKOC_1674086

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674086
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS02960

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 679 total members. Page 1 / 14.

GCF_000009205#CD630_RS02960 (representative)
CD630_RS02960 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000235905#HMPREF9945_RS15270
HMPREF9945_RS15270 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000448745#QC1_RS03525
QC1_RS03525 · HK · Classic
RefSeq: WP_021360160.1
GCF_000448845#QAQ_RS02275
QAQ_RS02275 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000448865#QAS_RS02345
QAS_RS02345 · HK · Classic
RefSeq: WP_021360160.1
GCF_000448885#QAU_RS02450
QAU_RS02450 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000448985#QCC_RS02325
QCC_RS02325 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449105#QCO_RS21120
QCO_RS21120 · HK · Classic
RefSeq: WP_330374633.1
GCF_000449205#QMQ_RS02585
QMQ_RS02585 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449225#QCY_RS02805
QCY_RS02805 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449245#QEA_RS02765
QEA_RS02765 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449365#QEQ_RS02750
QEQ_RS02750 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449485#QG3_RS02235
QG3_RS02235 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449545#QG9_RS02480
QG9_RS02480 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449665#QGG_RS02140
QGG_RS02140 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449685#QGK_RS02420
QGK_RS02420 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449725#QGO_RS02370
QGO_RS02370 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449805#QGY_RS01885
QGY_RS01885 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449825#QI3_RS02545
QI3_RS02545 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449925#QIE_RS02650
QIE_RS02650 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000449985#QIK_RS03545
QIK_RS03545 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450045#QIS_RS03180
QIS_RS03180 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450085#QIW_RS20950
QIW_RS20950 · HK · Classic
RefSeq: WP_021392152.1
GCF_000450105#QIY_RS02545
QIY_RS02545 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450125#QK1_RS15800
QK1_RS15800 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450305#QKK_RS02735
QKK_RS02735 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450345#QKO_RS02675
QKO_RS02675 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450365#QKQ_RS03050
QKQ_RS03050 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450385#QKS_RS02460
QKS_RS02460 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450425#QKW_RS02730
QKW_RS02730 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450485#QM3_RS02535
QM3_RS02535 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450505#QM5_RS02805
QM5_RS02805 · HK · Classic
RefSeq: WP_021360160.1
GCF_000450525#QM7_RS02565
QM7_RS02565 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450585#QMC_RS02440
QMC_RS02440 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450645#QSA_RS03335
QSA_RS03335 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450705#QMW_RS03040
QMW_RS03040 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450845#QOI_RS02310
QOI_RS02310 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450905#QQI_RS02265
QQI_RS02265 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000450965#QQQ_RS02440
QQQ_RS02440 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451145#QQ1_RS02160
QQ1_RS02160 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451205#QE5_RS02810
QE5_RS02810 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451245#QE9_RS02270
QE9_RS02270 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451265#QOW_RS02015
QOW_RS02015 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451385#QQ5_RS02640
QQ5_RS02640 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451505#QQA_RS02250
QQA_RS02250 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451545#QQE_RS02910
QQE_RS02910 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451565#QQO_RS02570
QQO_RS02570 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451745#QSK_RS02365
QSK_RS02365 · HK · Classic
RefSeq: WP_021360160.1
GCF_000451825#QSU_RS15510
QSU_RS15510 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3
GCF_000451925#QU9_RS02140
QU9_RS02140 · HK · Classic
RefSeq: WP_003434751.1
UniProt: Q188S3

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021284275
AssemblyASM2128427v1 · Contighaploid
Genome composition4 238 945 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 53CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key