1 HAMP#1
132-205 aa · 74 aa · 16.8% of protein
Raw token
HAMP:132:0.00000000458:205:74:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWG76_RS07005
Histidine kinase, Classic
Clostridioides difficile · GCF_021283845
ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283845#LWG76_RS07005Stable P2CS identifier used across views.
GenomeGCF_021283845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 440 aa (56.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
Domain-by-domain annotation3 items
2 HisKA#2
216-281 aa · 66 aa · 15.0% of protein
Raw token
HisKA:216:0.0000000036:281:66:643 HATPase_c#3
331-437 aa · 107 aa · 24.3% of protein
Raw token
HATPase_c:331:1.83e-25:437:107:109- Raw architecture: HAMP:132:0.00000000458:205:74:69#HisKA:216:0.0000000036:281:66:64#HATPase_c:331:1.83e-25:437:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_021283845::NZ_JAJSMJ010000089.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2911-5046Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWG76_07005RefSeq proteinWP_331472205.1
Context group ID
GCF_021283845::NZ_JAJSMJ010000089.1::G00037Context members
LWG76_RS07000LWG76_RS07005
Partner locus tags
LWG76_RS07000LWG76_RS07005
Partner old locus tags
LWG76_07000LWG76_07005
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_331472205.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWG76_RS07005Primary locus identifier stored in the genes table.
Old locus tagLWG76_07005Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMJ010000089.1Sequence record reported by the local genomic context database.
Genomic interval3 724-5 046 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 911-5 046 ntGCF_021283845::NZ_JAJSMJ010000089.1::G00037
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021283845::NZ_JAJSMJ010000089.1::G00037Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMJ010000089.1All displayed genes belong to this local TCS context.
Neighborhood span2 911-5 046 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 911 nt5 046 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWG76_RS07000GCF_021283845#LWG76_RS07000
RROmpR
2 911-3 603 nt · Forward (+)
LWG76_RS07005GCF_021283845#LWG76_RS07005
HKClassicCurrent focus
3 724-5 046 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_021283845#LWG76_RS07005The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2077001
Simplified PFAM architecture for HKOC_2077001
PFAM domain coverage: 222 / 440 aa (50.5%)
1 aa440 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[155-204] | HisKA[217-281] | HATPase_c[331-437]
- Domain count: 3
- Matched identifier: HKOC_2077001
- Positioned domains: HAMP 155-204 ; HisKA 217-281 ; HATPase_c 331-437
Cluster members and taxonomy
Representative gene: GCF_021283845#LWG76_RS07005
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283845
AssemblyASM2128384v1 · Contighaploid
Genome composition3 861 163 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 48 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key