1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw token
H_kinase_N:12:7.33e-36:142:132:139P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE78_RS06500
Histidine kinase, Classic
Clostridioides difficile · GCF_021283745
ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283745#LWE78_RS06500Stable P2CS identifier used across views.
GenomeGCF_021283745Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
Domain-by-domain annotation3 items
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw token
HisKA_2:276:3.39e-17:350:76:763 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw token
HATPase_c:370:0.000000589:467:114:109- Raw architecture: H_kinase_N:12:7.33e-36:142:132:139#HisKA_2:276:3.39e-17:350:76:76#HATPase_c:370:0.000000589:467:114:109
- Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_021283745::NZ_JAJSOB010000043.1::G00050
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4721-6698Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE78_06500RefSeq proteinWP_003423979.1
Context group ID
GCF_021283745::NZ_JAJSOB010000043.1::G00050Context members
LWE78_RS06495LWE78_RS06500
Partner locus tags
LWE78_RS06495LWE78_RS06500
Partner old locus tags
LWE78_06495LWE78_06500
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003423979.1Primary protein accession used for annex mappings.
UniProt accessionD5Q482Primary UniProt accession resolved in the annex database.
UniProt IDD5Q482_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE78_RS06500Primary locus identifier stored in the genes table.
Old locus tagLWE78_06500Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSOB010000043.1Sequence record reported by the local genomic context database.
Genomic interval5 289-6 698 nt1 410 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 721-6 698 ntGCF_021283745::NZ_JAJSOB010000043.1::G00050
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021283745::NZ_JAJSOB010000043.1::G00050Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSOB010000043.1All displayed genes belong to this local TCS context.
Neighborhood span4 721-6 698 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 721 nt6 698 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWE78_RS06495GCF_021283745#LWE78_RS06495
RRAmiR_NasR
4 721-5 296 nt · Forward (+)
LWE78_RS06500GCF_021283745#LWE78_RS06500
HKClassicCurrent focus
5 289-6 698 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164175#HMPREF0220_RS14035Use this link to inspect the representative gene detail.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1727001
Simplified PFAM architecture for HKOC_1727001
PFAM domain coverage: 305 / 469 aa (65.0%)
1 aa469 aa
GAF_PdtaSHisKA_2HATPase_c
- Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
- Raw architecture: GAF_PdtaS[6-141] | HisKA_2[276-350] | HATPase_c[373-466]
- Domain count: 3
- Matched identifier: HKOC_1727001
- Positioned domains: GAF_PdtaS 6-141 ; HisKA_2 276-350 ; HATPase_c 373-466
Cluster members and taxonomy
Representative gene: GCF_000164175#HMPREF0220_RS14035
Displayed with 5 columns and 10 rows per page from the local display config.
Showing members 1 to 50 over 282 total members. Page 1 / 6.
GCF_000164175#HMPREF0220_RS14035 (representative) | ||||
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283745
AssemblyASM2128374v1 · Contighaploid
Genome composition3 912 665 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key