Gene detail

LWE87_RS03950

Histidine kinase, Classic

Clostridioides difficile · GCF_021283725

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283725#LWE87_RS03950Stable P2CS identifier used across views.
GenomeGCF_021283725Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1674770Run 6 · 100 sequences · id 100% · cov 80%
External referencesWP_021366131.1 · A0A069AYU6 · MIST4 LWE87_RS03950RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for LWE87_RS03950
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000182:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000219:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:2.57e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000182:238:78:69#HisKA:250:0.00000000219:315:66:64#HATPase_c:365:2.57e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021283725::NZ_JAJSMV010000034.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6919-9054Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE87_03950RefSeq proteinWP_021366131.1
Context group IDGCF_021283725::NZ_JAJSMV010000034.1::G00040
Context members
LWE87_RS03950LWE87_RS03955
Partner locus tags
LWE87_RS03950LWE87_RS03955
Partner old locus tags
LWE87_03950LWE87_03955
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366131.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AYU6Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AYU6_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE87_RS03950Primary locus identifier stored in the genes table.
Old locus tagLWE87_03950Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMV010000034.1Sequence record reported by the local genomic context database.
Genomic interval6 919-8 343 nt1 425 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span6 919-9 054 ntGCF_021283725::NZ_JAJSMV010000034.1::G00040

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021283725::NZ_JAJSMV010000034.1::G00040

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMV010000034.1All displayed genes belong to this local TCS context.
Neighborhood span6 919-9 054 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 919 nt9 054 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE87_RS03950GCF_021283725#LWE87_RS03950
HKClassicCurrent focus

6 919-8 343 nt · Reverse (-)

Old locus LWE87_03950RefSeq WP_021366131.1
LWE87_RS03955GCF_021283725#LWE87_RS03955
RROmpR

8 362-9 054 nt · Reverse (-)

Old locus LWE87_03955RefSeq WP_003434748.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1674770Run 6 · HK · 100 sequences
Representative sequenceGCF_000448765#QC5_RS02250Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1674770

Simplified PFAM architecture for HKOC_1674770

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1674770
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS02250

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 100 total members. Page 1 / 2.

GCF_000448765#QC5_RS02250 (representative)
QC5_RS02250 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_000449705#QGM_RS02235
QGM_RS02235 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_000452265#C673_RS02185
C673_RS02185 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_000452285#C674_RS02190
C674_RS02190 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_000452305#C675_RS02310
C675_RS02310 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_000452325#C676_RS02795
C676_RS02795 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_000473605#QSW_RS02600
QSW_RS02600 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_000586575#Y779_RS0102325
Y779_RS0102325 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_000939295#BN1097_RS02975
BN1097_RS02975 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_001192735#AWU81_RS03035
AWU81_RS03035 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_001263655#AWU80_RS17885
AWU80_RS17885 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_001263675#AWU78_RS18605
AWU78_RS18605 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_001263695#AWU79_RS13990
AWU79_RS13990 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_002301075#BGU05_RS12350
BGU05_RS12350 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_002301105#BGU08_RS04960
BGU08_RS04960 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_002302885#BGV09_RS00430
BGV09_RS00430 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_002303125#BGV22_RS06480
BGV22_RS06480 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_003481905#CDIF29688_RS03075
CDIF29688_RS03075 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_004314925#E0O72_RS03595
E0O72_RS03595 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_004315705#E0P69_RS14800
E0P69_RS14800 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_004315945#E0P54_RS17230
E0P54_RS17230 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_004316725#E0Q14_RS01190
E0Q14_RS01190 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_004317945#E0Q65_RS06935
E0Q65_RS06935 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_004318205#E0Q88_RS03225
E0Q88_RS03225 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_004319125#E0R36_RS03155
E0R36_RS03155 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_007000675#D1N83_RS12975
D1N83_RS12975 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_007000845#D1N73_RS13375
D1N73_RS13375 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_007000915#D1N70_RS14825
D1N70_RS14825 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_007000925#D1N68_RS02380
D1N68_RS02380 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_007000965#D1N69_RS07370
D1N69_RS07370 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_007001195#D1N57_RS09915
D1N57_RS09915 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_012030135#GSQ49_RS13655
GSQ49_RS13655 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_017310965#JQS20_RS16695
JQS20_RS16695 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_019426605#K1N11_RS09445
K1N11_RS09445 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_021283725#LWE87_RS03950
LWE87_RS03950 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_021283905#LWE93_RS11570
LWE93_RS11570 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_021284005#LWE88_RS01340
LWE88_RS01340 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_024451165#NO136_RS12480
NO136_RS12480 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_025135955#CDIF104450_RS03010
CDIF104450_RS03010 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_025533115#H3U19_RS15555
H3U19_RS15555 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_026337815#OSC44_RS02155
OSC44_RS02155 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_030251055#QQO49_RS02475
QQO49_RS02475 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_030251165#QQO35_RS05530
QQO35_RS05530 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_030251305#QQO58_RS02460
QQO58_RS02460 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_030251745#QQO64_RS03825
QQO64_RS03825 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_034188805#SQ131_RS16260
SQ131_RS16260 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_036698425#LFB09_RS13805
LFB09_RS13805 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_036698795#LFB08_RS15320
LFB08_RS15320 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_038753305#ABCP51_RS19695
ABCP51_RS19695 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6
GCF_042876425#ACFYIC_RS08790
ACFYIC_RS08790 · HK · Classic
RefSeq: WP_021366131.1
UniProt: A0A069AYU6

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283725
AssemblyASM2128372v1 · Contighaploid
Genome composition3 985 733 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key