Gene detail

LWE87_RS00285

Histidine kinase, Classic

Clostridioides difficile · GCF_021283725

ClassHKTypeClassicLength360 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283725#LWE87_RS00285Stable P2CS identifier used across views.
GenomeGCF_021283725Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2747088Run 6 · 193 sequences · id 100% · cov 80%
External referencesWP_021403563.1 · MIST4 LWE87_RS00285RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length360 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 360 aa (44.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for LWE87_RS00285
Domain-by-domain annotation2 items
1 HisKA#1
135-198 aa · 64 aa · 17.8% of protein
Raw tokenHisKA:135:0.000000000000315:198:64:64
2 HATPase_c#2
248-344 aa · 97 aa · 26.9% of protein
Raw tokenHATPase_c:248:4.3e-21:344:97:109
  • Raw architecture: HisKA:135:0.000000000000315:198:64:64#HATPase_c:248:4.3e-21:344:97:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021283725::NZ_JAJSMV010000002.1::G00050
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span9795-11628Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE87_00285RefSeq proteinWP_021403563.1
Context group IDGCF_021283725::NZ_JAJSMV010000002.1::G00050
Context members
LWE87_RS00280LWE87_RS00285
Partner locus tags
LWE87_RS00280LWE87_RS00285
Partner old locus tags
LWE87_00280LWE87_00285
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021403563.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE87_RS00285Primary locus identifier stored in the genes table.
Old locus tagLWE87_00285Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSMV010000002.1Sequence record reported by the local genomic context database.
Genomic interval10 546-11 628 nt1 083 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span9 795-11 628 ntGCF_021283725::NZ_JAJSMV010000002.1::G00050

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021283725::NZ_JAJSMV010000002.1::G00050

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSMV010000002.1All displayed genes belong to this local TCS context.
Neighborhood span9 795-11 628 nt1 834 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 795 nt11 628 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE87_RS00280GCF_021283725#LWE87_RS00280
RROmpR

9 795-10 496 nt · Forward (+)

Old locus LWE87_00280RefSeq WP_003436401.1
LWE87_RS00285GCF_021283725#LWE87_RS00285
HKClassicCurrent focus

10 546-11 628 nt · Forward (+)

Old locus LWE87_00285RefSeq WP_021403563.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2747088Run 6 · HK · 193 sequences
Representative sequenceGCF_000242355#MUI_RS0107365Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2747088

Simplified PFAM architecture for HKOC_2747088

PFAM domain coverage: 161 / 360 aa (44.7%)

1 aa360 aa
HisKA: 136-198 aaHisKAHATPase_c: 248-345 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[136-198] | HATPase_c[248-345]
  • Domain count: 2
  • Matched identifier: HKOC_2747088
  • Positioned domains: HisKA 136-198 ; HATPase_c 248-345
Cluster members and taxonomy
Visualization

Representative gene: GCF_000242355#MUI_RS0107365

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283725
AssemblyASM2128372v1 · Contighaploid
Genome composition3 985 733 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key