Gene detail

LWE91_RS05310

Histidine kinase, Classic

Clostridioides difficile · GCF_021283625

ClassHKTypeClassicLength254 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283625#LWE91_RS05310Stable P2CS identifier used across views.
GenomeGCF_021283625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2511819Run 6 · 229 sequences · id 100% · cov 80%
External referencesWP_223380601.1 · MIST4 LWE91_RS05310RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length254 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage166 / 254 aa (65.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for LWE91_RS05310
Domain-by-domain annotation2 items
1 HisKA#1
29-88 aa · 60 aa · 23.6% of protein
Raw tokenHisKA:29:0.00000000627:88:60:64
2 HATPase_c#2
145-250 aa · 106 aa · 41.7% of protein
Raw tokenHATPase_c:145:2.82e-29:250:106:109
  • Raw architecture: HisKA:29:0.00000000627:88:60:64#HATPase_c:145:2.82e-29:250:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_021283625::NZ_JAJSNB010000044.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span16244-18080Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE91_05310RefSeq proteinWP_223380601.1
Context group IDGCF_021283625::NZ_JAJSNB010000044.1::G00020
Context members
LWE91_RS05305LWE91_RS05310
Partner locus tags
LWE91_RS05305LWE91_RS05310
Partner old locus tags
LWE91_05305LWE91_05310
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_223380601.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLWE91_RS05310Primary locus identifier stored in the genes table.
Old locus tagLWE91_05310Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNB010000044.1Sequence record reported by the local genomic context database.
Genomic interval17 316-18 080 nt765 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span16 244-18 080 ntGCF_021283625::NZ_JAJSNB010000044.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_021283625::NZ_JAJSNB010000044.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNB010000044.1All displayed genes belong to this local TCS context.
Neighborhood span16 244-18 080 nt1 837 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
16 244 nt18 080 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LWE91_RS05305GCF_021283625#LWE91_RS05305
RROmpR

16 244-16 978 nt · Forward (+)

Old locus LWE91_05305RefSeq WP_003421230.1
LWE91_RS05310GCF_021283625#LWE91_RS05310
HKClassicCurrent focus

17 316-18 080 nt · Forward (+)

Old locus LWE91_05310RefSeq WP_223380601.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2511819Run 6 · HK · 229 sequences
Representative sequenceGCF_000582865#BN165_RS00200Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2511819

Simplified PFAM architecture for HKOC_2511819

PFAM domain coverage: 167 / 392 aa (42.6%)

1 aa392 aa
HisKA: 167-226 aaHisKAHATPase_c: 283-389 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[167-226] | HATPase_c[283-389]
  • Domain count: 2
  • Matched identifier: HKOC_2511819
  • Positioned domains: HisKA 167-226 ; HATPase_c 283-389
Cluster members and taxonomy
Visualization

Representative gene: GCF_000582865#BN165_RS00200

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283625
AssemblyASM2128362v1 · Contighaploid
Genome composition3 919 288 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 46 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key