1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw token
HisKA:82:0.0000000759:144:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
LWE91_RS00315
Histidine kinase, Classic
Clostridioides difficile · GCF_021283625
ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_021283625#LWE91_RS00315Stable P2CS identifier used across views.
GenomeGCF_021283625Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 302 aa (55.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
192-295 aa · 104 aa · 34.4% of protein
Raw token
HATPase_c:192:8.03e-23:295:104:109- Raw architecture: HisKA:82:0.0000000759:144:63:64#HATPase_c:192:8.03e-23:295:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_021283625::NZ_JAJSNB010000001.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span60270-61851Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLWE91_00315RefSeq proteinWP_003424113.1
Context group ID
GCF_021283625::NZ_JAJSNB010000001.1::G00025Context members
LWE91_RS00315LWE91_RS00320
Partner locus tags
LWE91_RS00315LWE91_RS00320
Partner old locus tags
LWE91_00315LWE91_00320
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003424113.1Primary protein accession used for annex mappings.
UniProt accessionD5Q437Primary UniProt accession resolved in the annex database.
UniProt IDD5Q437_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagLWE91_RS00315Primary locus identifier stored in the genes table.
Old locus tagLWE91_00315Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJSNB010000001.1Sequence record reported by the local genomic context database.
Genomic interval60 270-61 178 nt909 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span60 270-61 851 ntGCF_021283625::NZ_JAJSNB010000001.1::G00025
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_021283625::NZ_JAJSNB010000001.1::G00025Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJSNB010000001.1All displayed genes belong to this local TCS context.
Neighborhood span60 270-61 851 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
60 270 nt61 851 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
LWE91_RS00315GCF_021283625#LWE91_RS00315
HKClassicCurrent focus
60 270-61 178 nt · Reverse (-)
LWE91_RS00320GCF_021283625#LWE91_RS00320
RROmpR
61 180-61 851 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0209400Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2884672
Simplified PFAM architecture for HKOC_2884672
PFAM domain coverage: 168 / 302 aa (55.6%)
1 aa302 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[82-144] | HATPase_c[192-296]
- Domain count: 2
- Matched identifier: HKOC_2884672
- Positioned domains: HisKA 82-144 ; HATPase_c 192-296
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0209400
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_021283625
AssemblyASM2128362v1 · Contighaploid
Genome composition3 919 288 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 94 · HK 46 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key