Gene detail

LKD46_RS03880

Histidine kinase, Classic

Blautia fusiformis · GCF_020686995

ClassHKTypeClassicLength595 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_020686995#LKD46_RS03880Stable P2CS identifier used across views.
GenomeGCF_020686995Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1079712Run 6 · 47 sequences · id 100% · cov 80%
External referencesWP_015527303.1 · A0AAW5CII6 · MIST4 LKD46_RS03880RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length595 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage500 / 595 aa (84.0%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa595 aa
dCache_1: 46-286 aa (241 aa)1HAMP: 305-374 aa (70 aa)2His_kinase: 389-468 aa (80 aa)3HATPase_c: 480-588 aa (109 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
46-286 aa · 241 aa · 40.5% of protein
Raw tokendCache_1:46:3.91e-22:286:246:195
2 HAMP#2
305-374 aa · 70 aa · 11.8% of protein
Raw tokenHAMP:305:0.0000000000000108:374:70:69
3 His_kinase#3
389-468 aa · 80 aa · 13.4% of protein
Raw tokenHis_kinase:389:7.58e-34:468:80:80
4 HATPase_c#4
480-588 aa · 109 aa · 18.3% of protein
Raw tokenHATPase_c:480:0.00000000000000177:588:113:109
  • Raw architecture: dCache_1:46:3.91e-22:286:246:195#HAMP:305:0.0000000000000108:374:70:69#His_kinase:389:7.58e-34:468:80:80#HATPase_c:480:0.00000000000000177:588:113:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_020686995::NZ_JAJEPT010000003.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span67786-71186Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLKD46_03890RefSeq proteinWP_015527303.1
Context group IDGCF_020686995::NZ_JAJEPT010000003.1::G00037
Context members
LKD46_RS03875LKD46_RS03880
Partner locus tags
LKD46_RS03875LKD46_RS03880
Partner old locus tags
LKD46_03885LKD46_03890
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_015527303.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW5CII6Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW5CII6_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLKD46_RS03880Primary locus identifier stored in the genes table.
Old locus tagLKD46_03890Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJEPT010000003.1Sequence record reported by the local genomic context database.
Genomic interval69 399-71 186 nt1 788 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span67 786-71 186 ntGCF_020686995::NZ_JAJEPT010000003.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_020686995::NZ_JAJEPT010000003.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJEPT010000003.1All displayed genes belong to this local TCS context.
Neighborhood span67 786-71 186 nt3 401 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
67 786 nt71 186 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LKD46_RS03875GCF_020686995#LKD46_RS03875
RRunclassified

67 786-69 402 nt · Forward (+)

Old locus LKD46_03885RefSeq WP_059086074.1
LKD46_RS03880GCF_020686995#LKD46_RS03880
HKClassicCurrent focus

69 399-71 186 nt · Forward (+)

Old locus LKD46_03890RefSeq WP_015527303.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1079712Run 6 · HK · 47 sequences
Representative sequenceGCF_000209835#CK1_RS16660Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1079712

Simplified PFAM architecture for HKOC_1079712

PFAM domain coverage: 471 / 595 aa (79.2%)

1 aa595 aa
dCache_1: 55-286 aadCache_1HAMP: 321-374 aaHAMPHis_kinase: 389-468 aaHis_kinaseHATPase_c: 484-588 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[55-286] | HAMP[321-374] | His_kinase[389-468] | HATPase_c[484-588]
  • Domain count: 4
  • Matched identifier: HKOC_1079712
  • Positioned domains: dCache_1 55-286 ; HAMP 321-374 ; His_kinase 389-468 ; HATPase_c 484-588
Cluster members and taxonomy
Visualization

Representative gene: GCF_000209835#CK1_RS16660

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 881 264 · GCF_020686995
AssemblyASM2068699v1 · Contigreference genome · haploid
Genome composition3 534 643 bp · 44,0% GCBlautia fusiformis
Signal transduction countsGenes 91 · HK 41 · RR 48CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key