Gene detail

LIP74_RS10490

Histidine kinase, Classic

Anaerostipes hadrus · GCF_020537325

ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_020537325#LIP74_RS10490Stable P2CS identifier used across views.
GenomeGCF_020537325Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_1504336Run 6 · 46 sequences · id 100% · cov 80%
External referencesWP_009265585.1 · D4MUY3 · MIST4 LIP74_RS10490RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 495 aa (49.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
HAMP: 184-252 aa (69 aa)1HisKA: 263-330 aa (68 aa)2HATPase_c: 377-485 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
184-252 aa · 69 aa · 13.9% of protein
Raw tokenHAMP:184:6.81e-16:252:69:69
2 HisKA#2
263-330 aa · 68 aa · 13.7% of protein
Raw tokenHisKA:263:8.3e-16:330:68:64
3 HATPase_c#3
377-485 aa · 109 aa · 22.0% of protein
Raw tokenHATPase_c:377:5.28e-32:485:109:109
  • Raw architecture: HAMP:184:6.81e-16:252:69:69#HisKA:263:8.3e-16:330:68:64#HATPase_c:377:5.28e-32:485:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_020537325::NZ_JAJBMH010000023.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span35785-37963Genomic interval covered by the local TCS group.
Identifiers
Old locus tagLIP74_10475RefSeq proteinWP_009265585.1
Context group IDGCF_020537325::NZ_JAJBMH010000023.1::G00010
Context members
LIP74_RS10485LIP74_RS10490
Partner locus tags
LIP74_RS10485LIP74_RS10490
Partner old locus tags
LIP74_10470LIP74_10475
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009265585.1Primary protein accession used for annex mappings.
UniProt accessionD4MUY3Primary UniProt accession resolved in the annex database.
UniProt IDD4MUY3_ANAHADisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagLIP74_RS10490Primary locus identifier stored in the genes table.
Old locus tagLIP74_10475Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAJBMH010000023.1Sequence record reported by the local genomic context database.
Genomic interval36 476-37 963 nt1 488 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span35 785-37 963 ntGCF_020537325::NZ_JAJBMH010000023.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_020537325::NZ_JAJBMH010000023.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAJBMH010000023.1All displayed genes belong to this local TCS context.
Neighborhood span35 785-37 963 nt2 179 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
35 785 nt37 963 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

LIP74_RS10485GCF_020537325#LIP74_RS10485
RROmpR

35 785-36 474 nt · Reverse (-)

Old locus LIP74_10470RefSeq WP_008394129.1
LIP74_RS10490GCF_020537325#LIP74_RS10490
HKClassicCurrent focus

36 476-37 963 nt · Reverse (-)

Old locus LIP74_10475RefSeq WP_009265585.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1504336Run 6 · HK · 46 sequences
Representative sequenceGCF_000210695#CL2_RS11460Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1504336

Simplified PFAM architecture for HKOC_1504336

PFAM domain coverage: 228 / 495 aa (46.1%)

1 aa495 aa
HAMP: 199-251 aaHAMPHisKA: 264-329 aaHisKAHATPase_c: 378-486 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[199-251] | HisKA[264-329] | HATPase_c[378-486]
  • Domain count: 3
  • Matched identifier: HKOC_1504336
  • Positioned domains: HAMP 199-251 ; HisKA 264-329 ; HATPase_c 378-486
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210695#CL2_RS11460

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_020537325
AssemblyASM2053732v1 · Contighaploid
Genome composition3 242 192 bp · 37,0% GCAnaerostipes hadrus
Signal transduction countsGenes 54 · HK 28 · RR 25CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key