1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000819:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1H40_RS16000
Histidine kinase, Classic
Clostridioides difficile · GCF_018884725
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_018884725#E1H40_RS16000Stable P2CS identifier used across views.
GenomeGCF_018884725Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:4.65e-30:668:104:109- Raw architecture: HisKA:449:0.00000000819:514:66:64#HATPase_c:565:4.65e-30:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labeltriadGCF_018884725::NZ_CP037811.1::G00050
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span3522105-3525599Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H40_16430RefSeq proteinWP_009906364.1
Context group ID
GCF_018884725::NZ_CP037811.1::G00050Context members
E1H40_RS15995E1H40_RS16000E1H40_RS16005
Partner locus tags
E1H40_RS15995E1H40_RS16000E1H40_RS16005
Partner old locus tags
E1H40_16425E1H40_16430E1H40_16435
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_009906364.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1H40_RS16000Primary locus identifier stored in the genes table.
Old locus tagE1H40_16430Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP037811.1Sequence record reported by the local genomic context database.
Genomic interval3 522 835-3 524 850 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 522 105-3 525 599 ntGCF_018884725::NZ_CP037811.1::G00050
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018884725::NZ_CP037811.1::G00050Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP037811.1All displayed genes belong to this local TCS context.
Neighborhood span3 522 105-3 525 599 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 522 105 nt3 525 599 nt
Neighborhood gene cards
3 genes in the current local neighborhood.
E1H40_RS15995GCF_018884725#E1H40_RS15995
RROmpR
3 522 105-3 522 785 nt · Reverse (-)
E1H40_RS16000GCF_018884725#E1H40_RS16000
HKClassicCurrent focus
3 522 835-3 524 850 nt · Reverse (-)
E1H40_RS16005GCF_018884725#E1H40_RS16005
RROmpR
3 524 922-3 525 599 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0216030Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842458
Simplified PFAM architecture for HKOC_0842458
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842458
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0216030
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018884725
AssemblyASM1888472v1 · Complete Genomehaploid
Genome composition3 936 124 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key