Gene detail

KH076_RS06935

Histidine kinase, Classic

Streptococcus sp. · GCF_018382235

ClassHKTypeClassicLength446 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018382235#KH076_RS06935Stable P2CS identifier used across views.
GenomeGCF_018382235Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Selected clusterHKOC_2015847Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_143567344.1 · MIST4 KH076_RS06935RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length446 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage350 / 446 aa (78.5%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa446 aa
HAMP: 13-79 aa (67 aa)1PAS: 93-197 aa (105 aa)2HisKA: 207-272 aa (66 aa)3HATPase_c: 325-436 aa (112 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
13-79 aa · 67 aa · 15.0% of protein
Raw tokenHAMP:13:0.000000467:79:67:69
2 PAS#2
93-197 aa · 105 aa · 23.5% of protein
Raw tokenPAS:93:0.0000000157:197:112:113
3 HisKA#3
207-272 aa · 66 aa · 14.8% of protein
Raw tokenHisKA:207:3.23e-16:272:66:64
4 HATPase_c#4
325-436 aa · 112 aa · 25.1% of protein
Raw tokenHATPase_c:325:5.53e-36:436:112:109
  • Raw architecture: HAMP:13:0.000000467:79:67:69#PAS:93:0.0000000157:197:112:113#HisKA:207:3.23e-16:272:66:64#HATPase_c:325:5.53e-36:436:112:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018382235::NZ_JAGZQI010000021.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18849-20892Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKH076_06940RefSeq proteinWP_143567344.1
Context group IDGCF_018382235::NZ_JAGZQI010000021.1::G00006
Context members
KH076_RS06935KH076_RS06940
Partner locus tags
KH076_RS06935KH076_RS06940
Partner old locus tags
KH076_06940KH076_06945
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_143567344.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKH076_RS06935Primary locus identifier stored in the genes table.
Old locus tagKH076_06940Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAGZQI010000021.1Sequence record reported by the local genomic context database.
Genomic interval18 849-20 189 nt1 341 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span18 849-20 892 ntGCF_018382235::NZ_JAGZQI010000021.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018382235::NZ_JAGZQI010000021.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGZQI010000021.1All displayed genes belong to this local TCS context.
Neighborhood span18 849-20 892 nt2 044 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 849 nt20 892 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

KH076_RS06935GCF_018382235#KH076_RS06935
HKClassicCurrent focus

18 849-20 189 nt · Reverse (-)

Old locus KH076_06940RefSeq WP_143567344.1
KH076_RS06940GCF_018382235#KH076_RS06940
RROmpR

20 182-20 892 nt · Reverse (-)

Old locus KH076_06945RefSeq WP_021145486.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2015847Run 6 · HK · 10 sequences
Representative sequenceGCF_018378445#KH262_RS08800Use this link to inspect the representative gene detail.
PFAM architectureCovS-like_HAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2015847

Simplified PFAM architecture for HKOC_2015847

PFAM domain coverage: 336 / 446 aa (75.3%)

1 aa446 aa
CovS-like_HAMP: 31-86 aaCovS-like_HAMPPAS: 94-197 aaPASHisKA: 208-272 aaHisKAHATPase_c: 325-435 aaHATPase_c
CovS-like_HAMPPASHisKAHATPase_c
  • Simplified architecture: CovS-like_HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: CovS-like_HAMP[31-86] | PAS[94-197] | HisKA[208-272] | HATPase_c[325-435]
  • Domain count: 4
  • Matched identifier: HKOC_2015847
  • Positioned domains: CovS-like_HAMP 31-86 ; PAS 94-197 ; HisKA 208-272 ; HATPase_c 325-435
Cluster members and taxonomy
Visualization

Representative gene: GCF_018378445#KH262_RS08800

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 306 · GCF_018382235
AssemblyASM1838223v1 · Contighaploid
Genome composition2 083 171 bp · 39,5% GCStreptococcus sp.
Signal transduction countsGenes 22 · HK 11 · RR 11CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus

Related genes

Preview from the same derived genome key