Gene detail

KH262_RS08800

Histidine kinase, Classic

Streptococcus sp. · GCF_018378445

ClassHKTypeClassicLength446 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018378445#KH262_RS08800Stable P2CS identifier used across views.
GenomeGCF_018378445Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Selected clusterHKOC_2015847Run 6 · 10 sequences · id 100% · cov 80% · representative
External referencesWP_143567344.1 · MIST4 KH262_RS08800RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length446 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage350 / 446 aa (78.5%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa446 aa
HAMP: 13-79 aa (67 aa)1PAS: 93-197 aa (105 aa)2HisKA: 207-272 aa (66 aa)3HATPase_c: 325-436 aa (112 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
13-79 aa · 67 aa · 15.0% of protein
Raw tokenHAMP:13:0.000000467:79:67:69
2 PAS#2
93-197 aa · 105 aa · 23.5% of protein
Raw tokenPAS:93:0.0000000157:197:112:113
3 HisKA#3
207-272 aa · 66 aa · 14.8% of protein
Raw tokenHisKA:207:3.23e-16:272:66:64
4 HATPase_c#4
325-436 aa · 112 aa · 25.1% of protein
Raw tokenHATPase_c:325:5.53e-36:436:112:109
  • Raw architecture: HAMP:13:0.000000467:79:67:69#PAS:93:0.0000000157:197:112:113#HisKA:207:3.23e-16:272:66:64#HATPase_c:325:5.53e-36:436:112:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018378445::NZ_JAGZXL010000018.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18849-20892Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKH262_08785RefSeq proteinWP_143567344.1
Context group IDGCF_018378445::NZ_JAGZXL010000018.1::G00007
Context members
KH262_RS08800KH262_RS08805
Partner locus tags
KH262_RS08800KH262_RS08805
Partner old locus tags
KH262_08785KH262_08790
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_143567344.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKH262_RS08800Primary locus identifier stored in the genes table.
Old locus tagKH262_08785Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAGZXL010000018.1Sequence record reported by the local genomic context database.
Genomic interval18 849-20 189 nt1 341 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span18 849-20 892 ntGCF_018378445::NZ_JAGZXL010000018.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018378445::NZ_JAGZXL010000018.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAGZXL010000018.1All displayed genes belong to this local TCS context.
Neighborhood span18 849-20 892 nt2 044 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 849 nt20 892 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

KH262_RS08800GCF_018378445#KH262_RS08800
HKClassicCurrent focus

18 849-20 189 nt · Reverse (-)

Old locus KH262_08785RefSeq WP_143567344.1
KH262_RS08805GCF_018378445#KH262_RS08805
RROmpR

20 182-20 892 nt · Reverse (-)

Old locus KH262_08790RefSeq WP_021145486.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2015847Run 6 · HK · 10 sequences
Representative sequenceGCF_018378445#KH262_RS08800The current gene is the representative for this cluster.
PFAM architectureCovS-like_HAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2015847

Simplified PFAM architecture for HKOC_2015847

PFAM domain coverage: 336 / 446 aa (75.3%)

1 aa446 aa
CovS-like_HAMP: 31-86 aaCovS-like_HAMPPAS: 94-197 aaPASHisKA: 208-272 aaHisKAHATPase_c: 325-435 aaHATPase_c
CovS-like_HAMPPASHisKAHATPase_c
  • Simplified architecture: CovS-like_HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: CovS-like_HAMP[31-86] | PAS[94-197] | HisKA[208-272] | HATPase_c[325-435]
  • Domain count: 4
  • Matched identifier: HKOC_2015847
  • Positioned domains: CovS-like_HAMP 31-86 ; PAS 94-197 ; HisKA 208-272 ; HATPase_c 325-435
Cluster members and taxonomy
Visualization

Representative gene: GCF_018378445#KH262_RS08800

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 306 · GCF_018378445
AssemblyASM1837844v1 · Contighaploid
Genome composition2 035 894 bp · 40,0% GCStreptococcus sp.
Signal transduction countsGenes 28 · HK 14 · RR 14CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus

Related genes

Preview from the same derived genome key