Gene detail

E1H42_RS01585

Response regulator OmpR family

Clostridioides difficile · GCF_018264045

ClassRRTypeOmpRLength226 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_018264045#E1H42_RS01585Stable P2CS identifier used across views.
GenomeGCF_018264045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_1407979Run 7 · 1738 sequences · id 100% · cov 80%
External referencesWP_003432361.1 · Q180B0 · MIST4 E1H42_RS01585RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length226 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage184 / 226 aa (81.4%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for E1H42_RS01585
Domain-by-domain annotation2 items
1 Response_reg#1
5-114 aa · 110 aa · 48.7% of protein
Raw tokenResponse_reg:5:1.52e-23:114:111:111
2 Trans_reg_C#2
150-223 aa · 74 aa · 32.7% of protein
Raw tokenTrans_reg_C:150:2.26e-22:223:75:77
  • Raw architecture: Response_reg:5:1.52e-23:114:111:111#Trans_reg_C:150:2.26e-22:223:75:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_018264045::NZ_SMNI01000001.1::G00003
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span342264-347987Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H42_01610RefSeq proteinWP_003432361.1
Context group IDGCF_018264045::NZ_SMNI01000001.1::G00003
Context members
E1H42_RS01575E1H42_RS01580E1H42_RS01585E1H42_RS01590E1H42_RS01595
Partner locus tags
E1H42_RS01575E1H42_RS01580E1H42_RS01585E1H42_RS01590E1H42_RS01595
Partner old locus tags
E1H42_01600E1H42_01605E1H42_01610E1H42_01615E1H42_01620

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003432361.1Primary protein accession used for annex mappings.
UniProt accessionQ180B0Primary UniProt accession resolved in the annex database.
UniProt IDQ180B0_CLOD6Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H42_RS01585Primary locus identifier stored in the genes table.
Old locus tagE1H42_01610Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNI01000001.1Sequence record reported by the local genomic context database.
Genomic interval345 078-345 758 nt681 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span342 264-347 987 ntGCF_018264045::NZ_SMNI01000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018264045::NZ_SMNI01000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span342 264-347 987 nt5 724 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
342 264 nt347 987 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

E1H42_RS01575GCF_018264045#E1H42_RS01575
RROmpR

342 264-342 941 nt · Forward (+)

Old locus E1H42_01600RefSeq WP_003417201.1
E1H42_RS01580GCF_018264045#E1H42_RS01580
HKClassic

343 013-345 028 nt · Forward (+)

Old locus E1H42_01605RefSeq WP_021422693.1
E1H42_RS01585GCF_018264045#E1H42_RS01585
RROmpRCurrent focus

345 078-345 758 nt · Forward (+)

Old locus E1H42_01610RefSeq WP_003432361.1
E1H42_RS01590GCF_018264045#E1H42_RS01590
RROmpR

346 138-346 836 nt · Forward (+)

Old locus E1H42_01615RefSeq WP_021422705.1
E1H42_RS01595GCF_018264045#E1H42_RS01595
HKClassic

346 872-347 987 nt · Forward (+)

Old locus E1H42_01620RefSeq WP_021397421.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_1407979Run 7 · RR · 1738 sequences
Representative sequenceGCF_000009205#CD630_RS17365Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_1407979

Simplified PFAM architecture for RROC_1407979

PFAM domain coverage: 183 / 226 aa (81.0%)

1 aa226 aa
Response_reg: 5-113 aaResponse_regResponse_reg: 5-113 aaResponse_regTrans_reg_C: 150-223 aaTrans_reg_CTrans_reg_C: 150-223 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[5-113] | Trans_reg_C[150-223]
  • Domain count: 2
  • Matched identifier: RROC_1407979
  • Positioned domains: Response_reg 5-113 ; Response_reg 5-113 ; Trans_reg_C 150-223 ; Trans_reg_C 150-223
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS17365

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264045
AssemblyASM1826404v1 · Contighaploid
Genome composition4 329 865 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 52 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key