1 HAMP#1
144-211 aa · 68 aa · 15.5% of protein
Raw token
HAMP:144:0.000000211:211:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1H42_RS01210
Histidine kinase, Classic
Clostridioides difficile · GCF_018264045
ClassHKTypeClassicLength439 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018264045#E1H42_RS01210Stable P2CS identifier used across views.
GenomeGCF_018264045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length439 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage211 / 439 aa (48.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
232-296 aa · 65 aa · 14.8% of protein
Raw token
HisKA:232:0.0000048:296:65:643 HATPase_c#3
342-419 aa · 78 aa · 17.8% of protein
Raw token
HATPase_c:342:0.00000544:419:90:109- Raw architecture: HAMP:144:0.000000211:211:68:69#HisKA:232:0.0000048:296:65:64#HATPase_c:342:0.00000544:419:90:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018264045::NZ_SMNI01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span258143-260112Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H42_01220RefSeq proteinWP_009889841.1
Context group ID
GCF_018264045::NZ_SMNI01000001.1::G00001Context members
E1H42_RS01205E1H42_RS01210
Partner locus tags
E1H42_RS01205E1H42_RS01210
Partner old locus tags
E1H42_01215E1H42_01220
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009889841.1Primary protein accession used for annex mappings.
UniProt accessionQ187J0Primary UniProt accession resolved in the annex database.
UniProt IDQ187J0_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1H42_RS01210Primary locus identifier stored in the genes table.
Old locus tagE1H42_01220Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNI01000001.1Sequence record reported by the local genomic context database.
Genomic interval258 793-260 112 nt1 320 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span258 143-260 112 ntGCF_018264045::NZ_SMNI01000001.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018264045::NZ_SMNI01000001.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span258 143-260 112 nt1 970 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
258 143 nt260 112 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1H42_RS01205GCF_018264045#E1H42_RS01205
RROmpR
258 143-258 796 nt · Forward (+)
E1H42_RS01210GCF_018264045#E1H42_RS01210
HKClassicCurrent focus
258 793-260 112 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0217010Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2082201
Simplified PFAM architecture for HKOC_2082201
PFAM domain coverage: 143 / 439 aa (32.6%)
1 aa439 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[233-296] | HATPase_c[342-420]
- Domain count: 2
- Matched identifier: HKOC_2082201
- Positioned domains: HisKA 233-296 ; HATPase_c 342-420
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0217010
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018264045
AssemblyASM1826404v1 · Contighaploid
Genome composition4 329 865 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 52 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key