Gene detail

E1H48_RS08635

Histidine kinase, Classic

Clostridioides difficile · GCF_018263955

ClassHKTypeClassicLength221 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018263955#E1H48_RS08635Stable P2CS identifier used across views.
GenomeGCF_018263955Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2928445Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_235699270.1 · MIST4 E1H48_RS08635RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length221 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage155 / 221 aa (70.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa221 aa
HisKA: 1-54 aa (54 aa)1HATPase_c: 110-210 aa (101 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
1-54 aa · 54 aa · 24.4% of protein
Raw tokenHisKA:1:0.0000997:54:59:64
2 HATPase_c#2
110-210 aa · 101 aa · 45.7% of protein
Raw tokenHATPase_c:110:1.13e-18:210:101:109
  • Raw architecture: HisKA:1:0.0000997:54:59:64#HATPase_c:110:1.13e-18:210:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018263955::NZ_SMNL01000001.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1929021-1930714Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H48_08805RefSeq proteinWP_235699270.1
Context group IDGCF_018263955::NZ_SMNL01000001.1::G00030
Context members
E1H48_RS08635E1H48_RS08640
Partner locus tags
E1H48_RS08635E1H48_RS08640
Partner old locus tags
E1H48_08805E1H48_08810
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_235699270.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H48_RS08635Primary locus identifier stored in the genes table.
Old locus tagE1H48_08805Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNL01000001.1Sequence record reported by the local genomic context database.
Genomic interval1 929 021-1 929 686 nt666 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 929 021-1 930 714 ntGCF_018263955::NZ_SMNL01000001.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018263955::NZ_SMNL01000001.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNL01000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 929 021-1 930 714 nt1 694 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 929 021 nt1 930 714 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1H48_RS08635GCF_018263955#E1H48_RS08635
HKClassicCurrent focus

1 929 021-1 929 686 nt · Reverse (-)

Old locus E1H48_08805RefSeq WP_235699270.1
E1H48_RS08640GCF_018263955#E1H48_RS08640
RROmpR

1 930 034-1 930 714 nt · Reverse (-)

Old locus E1H48_08810RefSeq WP_009903427.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2928445Run 6 · HK · 1 sequences
Representative sequenceGCF_018263955#E1H48_RS08635The current gene is the representative for this cluster.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2928445

Simplified PFAM architecture for HKOC_2928445

PFAM domain coverage: 105 / 221 aa (47.5%)

1 aa221 aa
HATPase_c: 105-209 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[105-209]
  • Domain count: 1
  • Matched identifier: HKOC_2928445
  • Positioned domains: HATPase_c 105-209
Cluster members and taxonomy
Visualization

Representative gene: GCF_018263955#E1H48_RS08635

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018263955
AssemblyASM1826395v1 · Contighaploid
Genome composition4 393 556 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 45 · RR 50CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key