1 HAMP#1
168-234 aa · 67 aa · 14.3% of protein
Raw token
HAMP:168:0.00000376:234:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E1H48_RS02060
Histidine kinase, Classic
Clostridioides difficile · GCF_018263955
ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018263955#E1H48_RS02060Stable P2CS identifier used across views.
GenomeGCF_018263955Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 469 aa (51.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
Domain-by-domain annotation3 items
2 HisKA#2
247-313 aa · 67 aa · 14.3% of protein
Raw token
HisKA:247:0.0000000000000196:313:67:643 HATPase_c#3
361-467 aa · 107 aa · 22.8% of protein
Raw token
HATPase_c:361:8.2e-27:467:108:109- Raw architecture: HAMP:168:0.00000376:234:69:69#HisKA:247:0.0000000000000196:313:67:64#HATPase_c:361:8.2e-27:467:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_018263955::NZ_SMNL01000001.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span436824-438962Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H48_02085RefSeq proteinWP_032508848.1
Context group ID
GCF_018263955::NZ_SMNL01000001.1::G00008Context members
E1H48_RS02055E1H48_RS02060
Partner locus tags
E1H48_RS02055E1H48_RS02060
Partner old locus tags
E1H48_02080E1H48_02085
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_032508848.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE1H48_RS02060Primary locus identifier stored in the genes table.
Old locus tagE1H48_02085Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNL01000001.1Sequence record reported by the local genomic context database.
Genomic interval437 553-438 962 nt1 410 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span436 824-438 962 ntGCF_018263955::NZ_SMNL01000001.1::G00008
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_018263955::NZ_SMNL01000001.1::G00008Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNL01000001.1All displayed genes belong to this local TCS context.
Neighborhood span436 824-438 962 nt2 139 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
436 824 nt438 962 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E1H48_RS02055GCF_018263955#E1H48_RS02055
RROmpR
436 824-437 549 nt · Forward (+)
E1H48_RS02060GCF_018263955#E1H48_RS02060
HKClassicCurrent focus
437 553-438 962 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_900164705#B2B36_RS18445Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1716470
Simplified PFAM architecture for HKOC_1716470
PFAM domain coverage: 172 / 471 aa (36.5%)
1 aa471 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[249-313] | HATPase_c[363-469]
- Domain count: 2
- Matched identifier: HKOC_1716470
- Positioned domains: HisKA 249-313 ; HATPase_c 363-469
Cluster members and taxonomy
Representative gene: GCF_900164705#B2B36_RS18445
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_018263955
AssemblyASM1826395v1 · Contighaploid
Genome composition4 393 556 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 45 · RR 50CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key