Gene detail

E1H48_RS02410

Histidine kinase, Classic

Clostridioides difficile · GCF_018263955

ClassHKTypeClassicLength637 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_018263955#E1H48_RS02410Stable P2CS identifier used across views.
GenomeGCF_018263955Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0860376Run 6 · 15 sequences · id 100% · cov 80%
External referencesWP_235699258.1 · MIST4 E1H48_RS02410RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length637 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage386 / 637 aa (60.6%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa637 aa
SBP_bac_3: 31-251 aa (221 aa)1HisKA: 419-481 aa (63 aa)2HATPase_c: 530-631 aa (102 aa)3
Domain-by-domain annotation3 items
1 SBP_bac_3#1
31-251 aa · 221 aa · 34.7% of protein
Raw tokenSBP_bac_3:31:1.21e-40:251:230:224
2 HisKA#2
419-481 aa · 63 aa · 9.9% of protein
Raw tokenHisKA:419:0.0000000000000451:481:63:64
3 HATPase_c#3
530-631 aa · 102 aa · 16.0% of protein
Raw tokenHATPase_c:530:1.39e-23:631:103:109
  • Raw architecture: SBP_bac_3:31:1.21e-40:251:230:224#HisKA:419:0.0000000000000451:481:63:64#HATPase_c:530:1.39e-23:631:103:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_018263955::NZ_SMNL01000001.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span502202-505437Genomic interval covered by the local TCS group.
Identifiers
Old locus tagE1H48_02450RefSeq proteinWP_235699258.1
Context group IDGCF_018263955::NZ_SMNL01000001.1::G00010
Context members
E1H48_RS02410E1H48_RS02415
Partner locus tags
E1H48_RS02410E1H48_RS02415
Partner old locus tags
E1H48_02450E1H48_02455
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_235699258.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE1H48_RS02410Primary locus identifier stored in the genes table.
Old locus tagE1H48_02450Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SMNL01000001.1Sequence record reported by the local genomic context database.
Genomic interval502 202-504 115 nt1 914 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span502 202-505 437 ntGCF_018263955::NZ_SMNL01000001.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_018263955::NZ_SMNL01000001.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SMNL01000001.1All displayed genes belong to this local TCS context.
Neighborhood span502 202-505 437 nt3 236 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
502 202 nt505 437 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E1H48_RS02410GCF_018263955#E1H48_RS02410
HKClassicCurrent focus

502 202-504 115 nt · Forward (+)

Old locus E1H48_02450RefSeq WP_235699258.1
E1H48_RS02415GCF_018263955#E1H48_RS02415
RRNtrC

504 115-505 437 nt · Forward (+)

Old locus E1H48_02455RefSeq WP_009893260.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0860376Run 6 · HK · 15 sequences
Representative sequenceGCF_000451665#QS3_RS08815Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0860376

Simplified PFAM architecture for HKOC_0860376

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0860376
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451665#QS3_RS08815

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_018263955
AssemblyASM1826395v1 · Contighaploid
Genome composition4 393 556 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 45 · RR 50CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key