Gene detail

CDIF101085_RS19295

Histidine kinase, Classic

Clostridioides difficile · GCF_015732535

ClassHKTypeClassicLength413 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015732535#CDIF101085_RS19295Stable P2CS identifier used across views.
GenomeGCF_015732535Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2330845Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_232879657.1 · MIST4 CDIF101085_RS19295RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length413 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 413 aa (41.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa413 aa
HisKA: 191-256 aa (66 aa)1HATPase_c: 307-410 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
191-256 aa · 66 aa · 16.0% of protein
Raw tokenHisKA:191:0.0000000143:256:66:64
2 HATPase_c#2
307-410 aa · 104 aa · 25.2% of protein
Raw tokenHATPase_c:307:8.84e-30:410:104:109
  • Raw architecture: HisKA:191:0.0000000143:256:66:64#HATPase_c:307:8.84e-30:410:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015732535::NZ_CP021319.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3601323-3603294Genomic interval covered by the local TCS group.
Context group IDGCF_015732535::NZ_CP021319.1::G00053
Context members
CDIF101085_RS16725CDIF101085_RS19295
Partner locus tags
CDIF101085_RS16725CDIF101085_RS19295
Partner old locus tags
CDIF101085_03449
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_232879657.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF101085_RS19295Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CP021319.1Sequence record reported by the local genomic context database.
Genomic interval3 602 053-3 603 294 nt1 242 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 601 323-3 603 294 ntGCF_015732535::NZ_CP021319.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015732535::NZ_CP021319.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP021319.1All displayed genes belong to this local TCS context.
Neighborhood span3 601 323-3 603 294 nt1 972 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 601 323 nt3 603 294 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDIF101085_RS16725GCF_015732535#CDIF101085_RS16725
RROmpR

3 601 323-3 602 003 nt · Reverse (-)

Old locus CDIF101085_03449RefSeq WP_003417207.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2330845Run 6 · HK · 4 sequences
Representative sequenceGCF_015732535#CDIF101085_RS19295The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2330845

Simplified PFAM architecture for HKOC_2330845

PFAM domain coverage: 170 / 413 aa (41.2%)

1 aa413 aa
HisKA: 192-256 aaHisKAHATPase_c: 305-409 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[192-256] | HATPase_c[305-409]
  • Domain count: 2
  • Matched identifier: HKOC_2330845
  • Positioned domains: HisKA 192-256 ; HATPase_c 305-409
Cluster members and taxonomy
Visualization

Representative gene: GCF_015732535#CDIF101085_RS19295

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_015732535
AssemblyASM1573253v1 · Complete Genomehaploid
Genome composition4 045 635 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key