Gene detail

I4U94_RS11460

Histidine kinase, Classic

Mediterraneibacter faecis · GCF_015669775

ClassHKTypeClassicLength581 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015669775#I4U94_RS11460Stable P2CS identifier used across views.
GenomeGCF_015669775Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1157130Run 6 · 2 sequences · id 100% · cov 80%
External referencesWP_081021275.1 · A0A174Z3G7 · MIST4 I4U94_RS11460RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length581 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 581 aa (44.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa581 aa
HAMP: 278-347 aa (70 aa)1His_kinase: 362-441 aa (80 aa)2HATPase_c: 458-565 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
278-347 aa · 70 aa · 12.0% of protein
Raw tokenHAMP:278:4.31e-17:347:70:69
2 His_kinase#2
362-441 aa · 80 aa · 13.8% of protein
Raw tokenHis_kinase:362:1.5e-32:441:80:80
3 HATPase_c#3
458-565 aa · 108 aa · 18.6% of protein
Raw tokenHATPase_c:458:1.88e-16:565:111:109
  • Raw architecture: HAMP:278:4.31e-17:347:70:69#His_kinase:362:1.5e-32:441:80:80#HATPase_c:458:1.88e-16:565:111:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015669775::NZ_JADPGZ010000011.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span83075-85517Genomic interval covered by the local TCS group.
Context group IDGCF_015669775::NZ_JADPGZ010000011.1::G00003
Context members
I4U94_RS11455I4U94_RS11460
Partner locus tags
I4U94_RS11455I4U94_RS11460
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_081021275.1Primary protein accession used for annex mappings.
UniProt accessionA0A174Z3G7Primary UniProt accession resolved in the annex database.
UniProt IDA0A174Z3G7_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI4U94_RS11460Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADPGZ010000011.1Sequence record reported by the local genomic context database.
Genomic interval83 772-85 517 nt1 746 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span83 075-85 517 ntGCF_015669775::NZ_JADPGZ010000011.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015669775::NZ_JADPGZ010000011.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADPGZ010000011.1All displayed genes belong to this local TCS context.
Neighborhood span83 075-85 517 nt2 443 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
83 075 nt85 517 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I4U94_RS11455GCF_015669775#I4U94_RS11455
RRunclassified

83 075-83 794 nt · Reverse (-)

RefSeq WP_020437167.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1157130Run 6 · HK · 2 sequences
Representative sequenceGCF_001406755#ARA59_RS01860Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1157130

Simplified PFAM architecture for HKOC_1157130

PFAM domain coverage: 237 / 581 aa (40.8%)

1 aa581 aa
HAMP: 296-347 aaHAMPHis_kinase: 362-441 aaHis_kinaseHATPase_c: 460-564 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[296-347] | His_kinase[362-441] | HATPase_c[460-564]
  • Domain count: 3
  • Matched identifier: HKOC_1157130
  • Positioned domains: HAMP 296-347 ; His_kinase 362-441 ; HATPase_c 460-564
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406755#ARA59_RS01860

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 592 978 · GCF_015669775
AssemblyASM1566977v1 · Scaffoldhaploid
Genome composition3 045 443 bp · 41,0% GCMediterraneibacter faecis
Signal transduction countsGenes 72 · HK 35 · RR 36CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key