Gene detail

I4U94_RS04420

Histidine kinase, Classic

Mediterraneibacter faecis · GCF_015669775

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015669775#I4U94_RS04420Stable P2CS identifier used across views.
GenomeGCF_015669775Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1749320Run 6 · 22 sequences · id 100% · cov 80%
External referencesWP_020437008.1 · A0A656CS31 · MIST4 I4U94_RS04420RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage239 / 467 aa (51.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 171-240 aa (70 aa)1HisKA: 245-304 aa (60 aa)2HATPase_c: 356-464 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
171-240 aa · 70 aa · 15.0% of protein
Raw tokenHAMP:171:0.0000000000066:240:70:69
2 HisKA#2
245-304 aa · 60 aa · 12.8% of protein
Raw tokenHisKA:245:0.0000000000000625:304:60:64
3 HATPase_c#3
356-464 aa · 109 aa · 23.3% of protein
Raw tokenHATPase_c:356:1.93e-31:464:109:109
  • Raw architecture: HAMP:171:0.0000000000066:240:70:69#HisKA:245:0.0000000000000625:304:60:64#HATPase_c:356:1.93e-31:464:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015669775::NZ_JADPGZ010000002.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span188393-190565Genomic interval covered by the local TCS group.
Context group IDGCF_015669775::NZ_JADPGZ010000002.1::G00028
Context members
I4U94_RS04415I4U94_RS04420
Partner locus tags
I4U94_RS04415I4U94_RS04420
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_020437008.1Primary protein accession used for annex mappings.
UniProt accessionA0A656CS31Primary UniProt accession resolved in the annex database.
UniProt IDA0A656CS31_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI4U94_RS04420Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADPGZ010000002.1Sequence record reported by the local genomic context database.
Genomic interval189 162-190 565 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span188 393-190 565 ntGCF_015669775::NZ_JADPGZ010000002.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015669775::NZ_JADPGZ010000002.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADPGZ010000002.1All displayed genes belong to this local TCS context.
Neighborhood span188 393-190 565 nt2 173 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
188 393 nt190 565 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I4U94_RS04415GCF_015669775#I4U94_RS04415
RROmpR

188 393-189 094 nt · Forward (+)

RefSeq WP_015527527.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1749320Run 6 · HK · 22 sequences
Representative sequenceGCF_001405415#ARA37_RS05375Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1749320

Simplified PFAM architecture for HKOC_1749320

PFAM domain coverage: 217 / 467 aa (46.5%)

1 aa467 aa
HAMP: 194-239 aaHAMPHisKA: 246-307 aaHisKAHATPase_c: 357-465 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[194-239] | HisKA[246-307] | HATPase_c[357-465]
  • Domain count: 3
  • Matched identifier: HKOC_1749320
  • Positioned domains: HAMP 194-239 ; HisKA 246-307 ; HATPase_c 357-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_001405415#ARA37_RS05375

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 592 978 · GCF_015669775
AssemblyASM1566977v1 · Scaffoldhaploid
Genome composition3 045 443 bp · 41,0% GCMediterraneibacter faecis
Signal transduction countsGenes 72 · HK 35 · RR 36CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key