1 HAMP#1
2-45 aa · 44 aa · 14.5% of protein
Raw token
HAMP:2:0.0000762:45:46:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
I2I25_RS00265
Histidine kinase, Classic
Mediterraneibacter gnavus · GCF_015561245
ClassHKTypeClassicLength304 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015561245#I2I25_RS00265Stable P2CS identifier used across views.
GenomeGCF_015561245Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length304 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage209 / 304 aa (68.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa304 aa
Domain-by-domain annotation3 items
2 HisKA#2
88-145 aa · 58 aa · 19.1% of protein
Raw token
HisKA:88:0.00000118:145:58:643 HATPase_c#3
192-298 aa · 107 aa · 35.2% of protein
Raw token
HATPase_c:192:3.31e-31:298:107:109- Raw architecture: HAMP:2:0.0000762:45:46:69#HisKA:88:0.00000118:145:58:64#HATPase_c:192:3.31e-31:298:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_015561245::NZ_JADMTD010000001.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span46548-48162Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_015561245::NZ_JADMTD010000001.1::G00016Context members
I2I25_RS00260I2I25_RS00265
Partner locus tags
I2I25_RS00260I2I25_RS00265
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_186279114.1Primary protein accession used for annex mappings.
UniProt accessionA0A564TIZ4Primary UniProt accession resolved in the annex database.
UniProt IDA0A564TIZ4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagI2I25_RS00265Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADMTD010000001.1Sequence record reported by the local genomic context database.
Genomic interval47 248-48 162 nt915 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span46 548-48 162 ntGCF_015561245::NZ_JADMTD010000001.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_015561245::NZ_JADMTD010000001.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADMTD010000001.1All displayed genes belong to this local TCS context.
Neighborhood span46 548-48 162 nt1 615 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
46 548 nt48 162 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
I2I25_RS00260GCF_015561245#I2I25_RS00260
RROmpR
46 548-47 246 nt · Forward (+)
I2I25_RS00265GCF_015561245#I2I25_RS00265
HKClassicCurrent focus
47 248-48 162 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_015561245#I2I25_RS00265The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2883426
Simplified PFAM architecture for HKOC_2883426
PFAM domain coverage: 166 / 304 aa (54.6%)
1 aa304 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[84-142] | HATPase_c[193-299]
- Domain count: 2
- Matched identifier: HKOC_2883426
- Positioned domains: HisKA 84-142 ; HATPase_c 193-299
Cluster members and taxonomy
Representative gene: GCF_015561245#I2I25_RS00265
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 33 038 · GCF_015561245
AssemblyASM1556124v1 · Scaffoldhaploid
Genome composition4 015 667 bp · 41,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 95 · HK 45 · RR 49CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter
Related genes
Preview from the same derived genome key