Gene detail

I2I31_RS02805

Histidine kinase, Hybrid

[Clostridium] symbiosum · GCF_015560355

ClassHKTypeHybridLength1199 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_015560355#I2I31_RS02805Stable P2CS identifier used across views.
GenomeGCF_015560355Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0159844Run 6 · 19 sequences · id 100% · cov 80%
External referencesWP_150028465.1 · A0AAW6APY6 · MIST4 I2I31_RS02805RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length1199 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage583 / 1199 aa (48.6%)Merged over positioned domains only.
Domain description2 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1199 aa
PAS_3: 178-259 aa (82 aa)1PAS_3: 300-384 aa (85 aa)2HisKA: 683-749 aa (67 aa)3HATPase_c: 796-913 aa (118 aa)4Response_reg: 936-1049 aa (114 aa)5Response_reg: 1076-1192 aa (117 aa)6
Domain-by-domain annotation6 items
1 PAS_3#1
178-259 aa · 82 aa · 6.8% of protein
Raw tokenPAS_3:178:4.39e-17:259:82:89
2 PAS_3#2
300-384 aa · 85 aa · 7.1% of protein
Raw tokenPAS_3:300:6.94e-16:384:85:89
3 HisKA#3
683-749 aa · 67 aa · 5.6% of protein
Raw tokenHisKA:683:0.00000000000000141:749:67:64
4 HATPase_c#4
796-913 aa · 118 aa · 9.8% of protein
Raw tokenHATPase_c:796:1.68e-29:913:119:109
5 Response_reg#5
936-1049 aa · 114 aa · 9.5% of protein
Raw tokenResponse_reg:936:3.86e-20:1049:114:111
6 Response_reg#6
1076-1192 aa · 117 aa · 9.8% of protein
Raw tokenResponse_reg:1076:5.69e-29:1192:117:111
  • Raw architecture: PAS_3:178:4.39e-17:259:82:89#PAS_3:300:6.94e-16:384:85:89#HisKA:683:0.00000000000000141:749:67:64#HATPase_c:796:1.68e-29:913:119:109#Response_reg:936:3.86e-20:1049:114:111#Response_reg:1076:5.69e-29:1192:117:111
  • Domain description: 2 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_015560355::NZ_JADMRR010000004.1::G00046
Group size33 locus tags listed below.
HK / RR2 / 1Counts resolved for the local TCS neighborhood.
Context span104480-113823Genomic interval covered by the local TCS group.
Context group IDGCF_015560355::NZ_JADMRR010000004.1::G00046
Context members
I2I31_RS02800I2I31_RS02805I2I31_RS02810
Partner locus tags
I2I31_RS02800I2I31_RS02805I2I31_RS02810

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_150028465.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW6APY6Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW6APY6_CLOSYDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2I31_RS02805Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADMRR010000004.1Sequence record reported by the local genomic context database.
Genomic interval107 654-111 235 nt3 582 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span104 480-113 823 ntGCF_015560355::NZ_JADMRR010000004.1::G00046

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015560355::NZ_JADMRR010000004.1::G00046

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADMRR010000004.1All displayed genes belong to this local TCS context.
Neighborhood span104 480-113 823 nt9 344 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
104 480 nt113 823 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

I2I31_RS02800GCF_015560355#I2I31_RS02800
HKHybrid

104 480-107 641 nt · Reverse (-)

RefSeq WP_150028428.1
I2I31_RS02810GCF_015560355#I2I31_RS02810
RRPleD_VieA

111 241-113 823 nt · Reverse (-)

RefSeq WP_156684466.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0159844Run 6 · HK · 19 sequences
Representative sequenceGCF_008632235#F2P57_RS20155Use this link to inspect the representative gene detail.
PFAM architecturePAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg6 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0159844

Simplified PFAM architecture for HKOC_0159844

PFAM domain coverage: 580 / 1199 aa (48.4%)

1 aa1199 aa
PAS_3: 178-260 aaPAS_3PAS_3: 302-384 aaPAS_3HisKA: 683-749 aaHisKAHATPase_c: 796-911 aaHATPase_cResponse_reg: 936-1049 aaResponse_regResponse_reg: 1076-1192 aaResponse_reg
PAS_3PAS_3HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_3[178-260] | PAS_3[302-384] | HisKA[683-749] | HATPase_c[796-911] | Response_reg[936-1049] | Response_reg[1076-1192]
  • Domain count: 6
  • Matched identifier: HKOC_0159844
  • Positioned domains: PAS_3 178-260 ; PAS_3 302-384 ; HisKA 683-749 ; HATPase_c 796-911 ; Response_reg 936-1049 ; Response_reg 1076-1192
Cluster members and taxonomy
Visualization

Representative gene: GCF_008632235#F2P57_RS20155

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 512 · GCF_015560355
AssemblyASM1556035v1 · Scaffoldhaploid
Genome composition5 439 051 bp · 48,0% GC[Clostridium] symbiosum
Signal transduction countsGenes 115 · HK 57 · RR 55CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key