Gene detail

I2E60_RS14740

Histidine kinase, Hybrid

Anaerostipes hadrus · GCF_015554695

ClassHKTypeHybridLength726 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_015554695#I2E60_RS14740Stable P2CS identifier used across views.
GenomeGCF_015554695Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_0721745Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_195466157.1 · MIST4 I2E60_RS14740RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length726 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage297 / 726 aa (40.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa726 aa
HisKA: 345-410 aa (66 aa)1HATPase_c: 463-576 aa (114 aa)2Response_reg: 599-715 aa (117 aa)3
Domain-by-domain annotation3 items
1 HisKA#1
345-410 aa · 66 aa · 9.1% of protein
Raw tokenHisKA:345:0.0000000000000272:410:66:64
2 HATPase_c#2
463-576 aa · 114 aa · 15.7% of protein
Raw tokenHATPase_c:463:1.63e-27:576:114:109
3 Response_reg#3
599-715 aa · 117 aa · 16.1% of protein
Raw tokenResponse_reg:599:4.07e-27:715:117:111
  • Raw architecture: HisKA:345:0.0000000000000272:410:66:64#HATPase_c:463:1.63e-27:576:114:109#Response_reg:599:4.07e-27:715:117:111
  • Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_015554695::NZ_JADNJB010000051.1::G00024
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span11754-13934Genomic interval covered by the local TCS group.
Context group IDGCF_015554695::NZ_JADNJB010000051.1::G00024
Context members
I2E60_RS14740
Partner locus tags
I2E60_RS14740
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_195466157.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2E60_RS14740Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADNJB010000051.1Sequence record reported by the local genomic context database.
Genomic interval11 754-13 934 nt2 181 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 754-13 934 ntGCF_015554695::NZ_JADNJB010000051.1::G00024

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015554695::NZ_JADNJB010000051.1::G00024

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADNJB010000051.1All displayed genes belong to this local TCS context.
Neighborhood span11 754-13 934 nt2 181 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 754 nt13 934 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0721745Run 6 · HK · 2 sequences
Representative sequenceGCF_015554695#I2E60_RS14740The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0721745

Simplified PFAM architecture for HKOC_0721745

PFAM domain coverage: 296 / 726 aa (40.8%)

1 aa726 aa
HisKA: 345-410 aaHisKAHATPase_c: 463-575 aaHATPase_cResponse_reg: 599-715 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[345-410] | HATPase_c[463-575] | Response_reg[599-715]
  • Domain count: 3
  • Matched identifier: HKOC_0721745
  • Positioned domains: HisKA 345-410 ; HATPase_c 463-575 ; Response_reg 599-715
Cluster members and taxonomy
Visualization

Representative gene: GCF_015554695#I2E60_RS14740

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_015554695
AssemblyASM1555469v1 · Scaffoldhaploid
Genome composition3 245 115 bp · 36,5% GCAnaerostipes hadrus
Signal transduction countsGenes 53 · HK 28 · RR 24CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key