Gene detail

I2D66_RS12940

Histidine kinase, Classic

Dorea longicatena · GCF_015553305

ClassHKTypeClassicLength614 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015553305#I2D66_RS12940Stable P2CS identifier used across views.
GenomeGCF_015553305Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_0992308Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_195369716.1 · MIST4 I2D66_RS12940RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1His_kinaseHATPase_c
Protein length614 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage379 / 614 aa (61.7%)Merged over positioned domains only.
Domain description1 dCache_1,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa614 aa
dCache_1: 95-285 aa (191 aa)1His_kinase: 385-464 aa (80 aa)2HATPase_c: 480-587 aa (108 aa)3
Domain-by-domain annotation3 items
1 dCache_1#1
95-285 aa · 191 aa · 31.1% of protein
Raw tokendCache_1:95:0.00000000000000267:285:197:195
2 His_kinase#2
385-464 aa · 80 aa · 13.0% of protein
Raw tokenHis_kinase:385:1.29e-33:464:80:80
3 HATPase_c#3
480-587 aa · 108 aa · 17.6% of protein
Raw tokenHATPase_c:480:6.67e-16:587:111:109
  • Raw architecture: dCache_1:95:0.00000000000000267:285:197:195#His_kinase:385:1.29e-33:464:80:80#HATPase_c:480:6.67e-16:587:111:109
  • Domain description: 1 dCache_1,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015553305::NZ_JADNGJ010000107.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17133-20608Genomic interval covered by the local TCS group.
Context group IDGCF_015553305::NZ_JADNGJ010000107.1::G00029
Context members
I2D66_RS12935I2D66_RS12940
Partner locus tags
I2D66_RS12935I2D66_RS12940
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_195369716.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI2D66_RS12940Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_JADNGJ010000107.1Sequence record reported by the local genomic context database.
Genomic interval18 764-20 608 nt1 845 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span17 133-20 608 ntGCF_015553305::NZ_JADNGJ010000107.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015553305::NZ_JADNGJ010000107.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADNGJ010000107.1All displayed genes belong to this local TCS context.
Neighborhood span17 133-20 608 nt3 476 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 133 nt20 608 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I2D66_RS12935GCF_015553305#I2D66_RS12935
RRunclassified

17 133-18 731 nt · Forward (+)

RefSeq WP_055182361.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0992308Run 6 · HK · 4 sequences
Representative sequenceGCF_015553305#I2D66_RS12940The current gene is the representative for this cluster.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0992308

Simplified PFAM architecture for HKOC_0992308

PFAM domain coverage: 414 / 614 aa (67.4%)

1 aa614 aa
dCache_1: 59-284 aadCache_1His_kinase: 385-464 aaHis_kinaseHATPase_c: 481-588 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[59-284] | His_kinase[385-464] | HATPase_c[481-588]
  • Domain count: 3
  • Matched identifier: HKOC_0992308
  • Positioned domains: dCache_1 59-284 ; His_kinase 385-464 ; HATPase_c 481-588
Cluster members and taxonomy
Visualization

Representative gene: GCF_015553305#I2D66_RS12940

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 88 431 · GCF_015553305
AssemblyASM1555330v1 · Contighaploid
Genome composition2 908 332 bp · 41,5% GCDorea longicatena
Signal transduction countsGenes 68 · HK 34 · RR 34CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key